{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T23:28:45Z","timestamp":1782602925520,"version":"3.54.5"},"reference-count":11,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,3,12]],"date-time":"2024-03-12T00:00:00Z","timestamp":1710201600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Australas J Ultrason Med"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A low\u2010grade appendiceal mucinous neoplasm (LAMN) is a cystic dilatation of the appendix resulting from the accumulation of mucinous secretions caused by a luminal obstruction. Although usually benign, pseudomyxoma peritonei may occur in the event of rupture, and 10% of cases may be secondary to appendiceal cystadenocarcinoma. A LAMN is both more common and more likely to have a malignant association in women, making it an entity with which practitioners of gynaecological ultrasound should be familiar. Although not the primary aim, early pregnancy ultrasound assessments can offer the diagnostic opportunity to identify pelvic pathology. A LAMN can be identified on ultrasonography by visualisation of an adnexal mass separate to the ovary, which due to the layers of secretions has a distinctive appearance previously likened to \u2018onion\u2010skin\u2019 or \u2018whipped\u2010cream\u2019. Here, we describe an incidental finding of a LAMN during an early pregnancy assessment. Practitioners of early pregnancy ultrasound should be familiar with the characteristic morphology of this rare but important finding.<\/jats:p>","DOI":"10.1002\/ajum.12377","type":"journal-article","created":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T01:40:05Z","timestamp":1710294005000},"page":"131-135","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The \u2018onion skin\u2019 sign of a low\u2010grade appendiceal mucinous neoplasm: An incidental finding during early pregnancy assessment"],"prefix":"10.1002","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4326-229X","authenticated-orcid":false,"given":"Hanine","family":"Fourie","sequence":"first","affiliation":[{"name":"Tommy's National Centre for Miscarriage Research Imperial College NHS Trust, Queen Charlotte and Chelsea Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3662-3010","authenticated-orcid":false,"given":"Maya","family":"Al Memar","sequence":"additional","affiliation":[{"name":"Tommy's National Centre for Miscarriage Research Imperial College NHS Trust, Queen Charlotte and Chelsea Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maeve","family":"Tuomey","sequence":"additional","affiliation":[{"name":"Tommy's National Centre for Miscarriage Research Imperial College NHS Trust, Queen Charlotte and Chelsea Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catriona","family":"Stalder","sequence":"additional","affiliation":[{"name":"Tommy's National Centre for Miscarriage Research Imperial College NHS Trust, Queen Charlotte and Chelsea Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Ziprin","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery Imperial College NHS Trust, St Mary's Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom","family":"Bourne","sequence":"additional","affiliation":[{"name":"Tommy's National Centre for Miscarriage Research Imperial College NHS Trust, Queen Charlotte and Chelsea Hospital  London UK"},{"name":"Department of Development and Regeneration KU Leuven  Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,3,12]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.1083"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1998.12010056.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00261-018-1561-9"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2004.23.1.117"},{"issue":"3","key":"e_1_2_8_6_1","first-page":"209","article-title":"Imaging in gynaecological disease: clinical and ultrasound characteristics of mucocele of the appendix. A pictorial essay","volume":"5","author":"Jansen E","year":"2013","journal-title":"Facts Views Vis Obgyn"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.138.6.585"},{"issue":"6","key":"e_1_2_8_8_1","first-page":"680","article-title":"A case of mucocele of the appendix resected in a pregnant woman","volume":"42","author":"Tanaka H","year":"2011","journal-title":"GSGS"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/01443615.2016.1209172"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10396-014-0527-y"},{"key":"e_1_2_8_11_1","first-page":"W590","article-title":"Appendiceal mucocele: a diagnostic dilemma in differentiating malignant from benign lesions with CT","volume":"201","author":"Wang H","year":"2012","journal-title":"Gastrointestinal Imaging"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1148\/rg.233025134"}],"container-title":["Australasian Journal of Ultrasound in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajum.12377","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,3]],"date-time":"2024-06-03T10:01:41Z","timestamp":1717408901000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajum.12377"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,12]]},"references-count":11,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,5]]}},"alternative-id":["10.1002\/ajum.12377"],"URL":"https:\/\/doi.org\/10.1002\/ajum.12377","archive":["Portico"],"relation":{},"ISSN":["1836-6864","2205-0140"],"issn-type":[{"value":"1836-6864","type":"print"},{"value":"2205-0140","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,12]]},"assertion":[{"value":"2024-03-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}