{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T13:57:51Z","timestamp":1773410271131,"version":"3.50.1"},"reference-count":34,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T00:00:00Z","timestamp":1713139200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Australas J Ultrason Med"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction\/Purpose<\/jats:title><jats:p>For gastric subepithelial lesions (GSELs) showing a hypoechoic mass (HM) on endoscopic ultrasonography (EUS) imaging, the utility of EUS\u2010guided tissue acquisition using conventional fine\u2010needle aspiration needles (EUS\u2010TA\u2010CFNAN) and the frequency of histological types remain unclear. This study aimed to examine this issue.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This prospective observational study enrolled 291 consecutive patients who underwent EUS\u2010TA\u2010CFNAN for GSELs showing an HM (GSELHM) on EUS imaging. Immunohistochemical analysis was performed for all EUS\u2010TA\u2010CFNAN and surgically resected specimens. The main outcome measures were the technical results of EUS\u2010TA\u2010CFNAN and the frequency of histological types in GSELHM.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The endoscopic ultrasound\u2010guided tissue acquisition using conventional fine\u2010needle aspiration needle diagnosis rate for GSELHM was 80.1% (95% confidence interval [CI]: 75.0\u201384.5, 233\/291). It was significantly lower for antrum (P\u2009=\u20090.004) and lesions smaller than 2\u2009cm (P\u2009=\u20090.003). There were no adverse events. The immunohistochemical diagnoses of EUS\u2010TA\u2010CFNAN included 149 cases of gastrointestinal stromal tumour (GIST) (51.2%), 48 cases of leiomyoma (16.5%), 11 cases of schwannoma (3.8%), 8 cases of the ectopic pancreas (2.7%), 5 cases of subepithelial lesion like cancer (1.7%), 12 cases of other lesions (4.1%), and 58 cases of undiagnosable lesions (19.9%). The frequency of malignant or potentially malignant tumour in GSELHM was 55.0% (95% CI: 49.1\u201360.8, 160\/291). Surgery was performed in 149 patients according to the conclusive EUS\u2010TA\u2010CFNAN results, in which the diagnostic accuracy of EUS\u2010TA\u2010CFNAN was 97.3% (95% CI: 94.7\u201399.9, 145\/149).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The use of EUS\u2010TA\u2010CFNAN for GSELHMs is safe and accurate. Gastric subepithelial lesions showing a hypoechoic mass have a reasonably high possibility of containing malignant or potentially malignant tumours, including GISTs.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ajum.12382","type":"journal-article","created":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T09:41:39Z","timestamp":1713174099000},"page":"89-96","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Efficacy and histologic frequencies of endoscopic ultrasonography\u2010guided tissue acquisition using conventional fine\u2010needle aspiration needles for gastric subepithelial hypoechoic mass"],"prefix":"10.1002","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1095-6546","authenticated-orcid":false,"given":"Kazuya","family":"Akahoshi","sequence":"first","affiliation":[{"name":"Endoscopy Center Aso Iizuka Hospital  Iizuka 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