{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T09:24:21Z","timestamp":1787649861463,"version":"build-2736575974"},"reference-count":59,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T00:00:00Z","timestamp":1786492800000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Australas J Ultrason Med"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The standard test to diagnose vocal cord palsy in adults is laryngoscopy, which is invasive, whereas laryngeal ultrasound (LUS) is an alternative, non\u2010invasive method. We conducted a systematic review to determine the accuracy of LUS in diagnosing VCP in adults.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>PubMed, EMBASE, CINAHL and Cochrane databases were searched in September 2025. We used a bivariate mixed\u2010effects regression model to conduct a meta\u2010analysis using Stata 18.0 software. We used the QUADAS\u20102 tool to assess the risk of bias and GRADE guidelines to assess the certainty of evidence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We included 41 studies (7818 patients) in the meta\u2010analysis. A total of 27 studies were performed in patients undergoing thyroid surgeries. The remaining 14 studies involved patients undergoing oesophageal surgery or routine laryngeal assessment or mediastinal surgeries. In 28 studies, blinding of at least one investigator was achieved. The pooled sensitivity of LUS for diagnosing VCP was 0.90 (95% CI: 0.85\u20130.93), with a specificity of 0.98 (95% CI: 0.97\u20130.99). The positive likelihood ratio (LR+) was 47.8 (95% CI 26.8\u201385.3) and the negative likelihood ratio (LR\u2010) was 0.10 (95% CI 0.07\u20130.16). The AUC for LUS was 0.98 (95% CI: 0.97\u20130.99). Certainty of evidence was graded as moderate in view of heterogeneity and the possibility of publication bias and lack of blinding in nearly 35% of the studies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Laryngeal ultrasound may be a useful tool to diagnose VCP in adults. Additional high\u2010quality studies meeting the stringent QUADAS\u20102 guidelines are needed to confirm these findings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ajum.70054","type":"journal-article","created":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T09:51:32Z","timestamp":1786528292000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Laryngeal Ultrasound for Vocal Cord Palsy in Adults: A Meta\u2010Analysis of Diagnostic Studies"],"prefix":"10.1002","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-2359-1028","authenticated-orcid":false,"given":"Uday S.","family":"Rao","sequence":"first","affiliation":[{"name":"Bunbury Regional Hospital  Bunbury Western Australia Australia"},{"name":"Royal Melbourne Hospital  Parkville Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8481-5925","authenticated-orcid":false,"given":"Shripada C.","family":"Rao","sequence":"additional","affiliation":[{"name":"School of Medicine University of Western Australia  Crawley Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,12]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/0145561320965212"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1308\/rcsann.2022.0091"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-1241.2008.01875.x"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/0145561319870487"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2020.102772"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10225393"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/ans.17530"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.5114\/pjr.2022.115154"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2021.08.019"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/jum.15884"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781119756194"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.19163"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.3348\/kjr.2015.16.6.1175"},{"key":"e_1_2_11_15_1","unstructured":"StataCorp \u201cStata Statistical Software: Release 18 \u201dCollege Station TX: StataCorp LLC (2023)."},{"key":"e_1_2_11_16_1","unstructured":"The Nordic Cochrane Centre TCC \u201cReview Manager (RevMan) [Computer Program] \u201dVersion 5.4. 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