{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T10:47:16Z","timestamp":1792061236708,"version":"4.4.0"},"reference-count":27,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2011,5,9]],"date-time":"2011-05-09T00:00:00Z","timestamp":1304899200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Forum Allergy Rhinol"],"published-print":{"date-parts":[[2011,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Endoscopic approaches of sinonasal malignancies are now being described. This study aims to conduct a systematic review with a pooled\u2010data analysis to compare outcomes of endoscopic vs craniofacial resection of sinonasal malignancies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A search was conducted of MEDLINE (1966\u20132008), EMBASE (1980\u20132008), Cochrane Central Register of Clinical Trials (CENTRAL), Cochrane Database of Systematic Reviews, clinicaltrials.gov, and The National Guideline Clearinghouse databases and supplemented by references in retrieved articles. All authors used a detailed list of inclusion and exclusion criteria to determine articles eligible for final inclusion. The authors extracted data regarding study criteria appraisal, sinonasal malignancy characteristics, survival outcomes, and recurrence. Kaplan\u2010Meier survival and locoregional control rates were calculated and compared using the log\u2010rank test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 2314 citations reviewed, the search yielded 15 case series with individual data on 226 patients. The most common malignancies were esthesioneuroblastoma (47%), adenocarcinoma (24%), and undifferentiated carcinoma (22%). The overall 5\u2010year survival rate for the sample was 56.5% (standard error [SE] \u00b1 3.8). Because of the paucity of data with endoscopic resection of high\u2010stage malignancies, the outcome results were highly variable and no useful comparison could be made. Among low\u2010stage malignancies (T1\u20132 or Kadish A\u2010B), the endoscopic and open approaches demonstrated no statistically significant difference in outcome results. The 5\u2010year overall survival was 87.4% (SE \u00b1 5.3) in the endoscopic group vs 76.8% (SE \u00b1 8.3) for open approaches (<jats:italic>p<\/jats:italic> = 0.351); disease\u2010specific survival was 94.7% (SE \u00b1 3.7) vs 87.7% (SE \u00b1 6.7; <jats:italic>p<\/jats:italic> = 0.258); and locoregional control rate was 89.5% (SE \u00b1 5.0) vs 77.2% (SE \u00b1 10.4; <jats:italic>p<\/jats:italic> = 0.251).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Transnasal endoscopic resection appears to be a reasonable alternative to craniofacial resection in the management of low\u2010stage sinonasal malignancies. \u00a9 2011 ARS\u2010AAOA, LLC.<\/jats:p><\/jats:sec>","DOI":"10.1002\/alr.20051","type":"journal-article","created":{"date-parts":[[2011,5,9]],"date-time":"2011-05-09T17:35:19Z","timestamp":1304962519000},"page":"255-261","source":"Crossref","is-referenced-by-count":66,"title":["Outcome results of endoscopic vs craniofacial resection of sinonasal malignancies: a systematic review and pooled\u2010data analysis"],"prefix":"10.1002","volume":"1","author":[{"given":"Thomas S.","family":"Higgins","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Thorp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brad A.","family":"Rawlings","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph K.","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,5,9]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2005.11.038"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00020840-200502000-00012"},{"key":"e_1_2_6_4_2","first-page":"199","article-title":"Possibilities and limitations of endoscopic management of nasal and paranasal sinus malignancies","volume":"53","author":"Stammberger H","year":"1999","journal-title":"Acta Otorhinolaryngol Belg."},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.2500\/ajr.2007.21.2957"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11912-007-0013-4"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/jso.21020"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-134-8-200104170-00012"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2003.10.010"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200312000-00005"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.SCS.0000164332.81428.BA"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2003.12.002"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2007.02.005"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2007.08.004"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1080\/0036554021000028080"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200008000-00007"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200208000-00023"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20168"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2007.01.016"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1177\/194589240501900317"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20748"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200004000-00018"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20193"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20771"},{"key":"e_1_2_6_25_2","first-page":"221","article-title":"Minimally invasive endoscopic management of malignant sinonasal tumours","volume":"54","author":"Goffart Y","year":"2000","journal-title":"Acta Otorhinolaryngol Belg."},{"key":"e_1_2_6_26_2","doi-asserted-by":"publisher","DOI":"10.2500\/ajr.2008.22.3170"},{"key":"e_1_2_6_27_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-134-4-200102200-00017"},{"key":"e_1_2_6_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2004.12.009"}],"container-title":["International Forum of Allergy &amp; 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