{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T22:04:50Z","timestamp":1759010690263},"reference-count":15,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2011,7,18]],"date-time":"2011-07-18T00:00:00Z","timestamp":1310947200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Forum Allergy Rhinol"],"published-print":{"date-parts":[[2011,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background:<\/jats:title><jats:p>Pathogenic bacteria have been cultured from the osteomeatal complex (OMC) in one\u2010third of adults with apparent acute bacterial sinusitis; however, it is not known whether bacteria are present in the OMC during uncomplicated viral colds in adults.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p>Adult volunteers were recruited for a study during wellness and at the time of acute common cold. Swab cultures were obtained from the OMC and from the nasopharynx by 2 routes (through the nose and through the mouth). Swab eluates were inoculated on selective agars to detect <jats:italic>S. pneumoniae<\/jats:italic>, <jats:italic>H. influenzae<\/jats:italic>, and <jats:italic>M. catarrhalis.<\/jats:italic><\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>Bacterial pathogens were detected in the OMC more frequently during common colds than during wellness (31% vs 8%, <jats:italic>p<\/jats:italic> &lt; 0.008). Pathogens detected in the OMC were always present in the nasopharynx of the subject.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p>Bacterial pathogens are present in the OMC in a subgroup of adult patients with uncomplicated upper respiratory illness\/common cold. The nasopharynx appears to be the reservoir for bacterial pathogens in the OMC. \u00a9 2011 ARS\u2010AAOA, LLC.<\/jats:p><\/jats:sec>","DOI":"10.1002\/alr.20080","type":"journal-article","created":{"date-parts":[[2011,7,18]],"date-time":"2011-07-18T14:49:33Z","timestamp":1311000573000},"page":"356-360","source":"Crossref","is-referenced-by-count":13,"title":["Bacterial pathogens of acute sinusitis in the osteomeatal complex during common colds and wellness"],"prefix":"10.1002","volume":"1","author":[{"given":"Joseph K.","family":"Han","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. 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