{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T05:37:34Z","timestamp":1785908254961,"version":"3.56.0"},"reference-count":21,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2013,7,10]],"date-time":"2013-07-10T00:00:00Z","timestamp":1373414400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Forum Allergy Rhinol"],"published-print":{"date-parts":[[2013,10]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Total intravenous anesthesia (TIVA) has been shown in some studies to impact visual field, blood loss, and cardiovascular parameters during endoscopic sinus surgery when compared to inhalational anesthesia (IA). These variables are critical in endoscopic sinus surgery. A systematic review and meta\u2010analysis was undertaken to discern the impact of TIVA vs IA in endoscopic sinus surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>MEDLINE (1950 to October 20, 2012) was searched using a search strategy designed to include all randomized controlled trials (RCTs) that discussed TIVA, IA, and endoscopic sinus surgery. An abstract search was then used to identify RCTs directly comparing TIVA and IA in endoscopic sinus surgery. All articles selected then underwent full\u2010text review. Data on visual field scores, blood loss, and cardiovascular parameters was then extracted, compared, and analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 42 articles identified by the search strategy. Full\u2010text review identified 9 articles that met eligibility criteria and contained extractable data. Although inconsistently reported, preoperative characteristics (Lund\u2010Mackay scores and history of nasal polyps) were similar (<jats:italic>p<\/jats:italic> &gt; 0.05) between the 2 groups. No difference was found between heart rate, mean arterial pressure, anesthesia time, operative time, or estimated blood loss. Only 7 studies reported a visibility score, but overall favored the TIVA group (<jats:italic>p<\/jats:italic> &lt; 0.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Current evidence supporting TIVA is limited to a handful of inconsistently controlled and reported studies. Standardized grading of visibility scores and preoperative characteristics would better establish the role of TIVA in endoscopic sinus surgery.<\/jats:p><\/jats:sec>","DOI":"10.1002\/alr.21196","type":"journal-article","created":{"date-parts":[[2013,7,10]],"date-time":"2013-07-10T14:08:43Z","timestamp":1373465323000},"page":"848-854","source":"Crossref","is-referenced-by-count":41,"title":["Systematic review and meta\u2010analysis of total intravenous anesthesia and endoscopic sinus surgery"],"prefix":"10.1002","volume":"3","author":[{"given":"Adam S.","family":"DeConde","sequence":"first","affiliation":[{"name":"Department of Head and Neck Surgery David Geffen School of Medicine, University of California, Los Angeles  Los Angeles CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher F.","family":"Thompson","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery David Geffen School of Medicine, University of California, Los Angeles  Los Angeles CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward C.","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery David Geffen School of Medicine, University of California, Los Angeles  Los Angeles CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey D.","family":"Suh","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery David Geffen School of Medicine, University of California, Los Angeles  Los Angeles CA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,7,10]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/194589240501900516"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aem304"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.21126"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0196-0709(93)90072-F"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200308000-00019"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0709(99)90018-2"},{"key":"e_1_2_7_8_1","first-page":"137","article-title":"Total intravenous anaesthesia in endoscopic sinus\u2010nasal surgery","volume":"24","author":"Tirelli G","year":"2004","journal-title":"Acta Otorhinolaryngol Ital"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.21125"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.4103\/0970-9185.83675"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2006.08.006"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2009.10.021"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.4097\/kjae.2010.59.6.377"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199302000-00017"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199701000-00010"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.20101"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03015479"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/MLG.0b013e318157f764"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.15.1.44"},{"key":"e_1_2_7_20_1","doi-asserted-by":"crossref","first-page":"59","DOI":"10.4103\/0970-9185.76649","article-title":"Comparison of propofol based anaesthesia to conventional inhalational general anaesthesia for spine surgery","volume":"27","author":"Mishra L","year":"2011","journal-title":"J Anaesthesiol Clin Pharmacol"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1213\/01.ANE.0000103187.70627.57"},{"key":"e_1_2_7_22_1","first-page":"324","article-title":"Blood loss in endoscopic sinus surgery: assessment of variables","volume":"37","author":"Laguna D","year":"2008","journal-title":"J Otolaryngol Head Neck Surg"}],"container-title":["International Forum of Allergy &amp; 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