{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T05:11:43Z","timestamp":1784265103784,"version":"3.55.0"},"reference-count":32,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2013,9,17]],"date-time":"2013-09-17T00:00:00Z","timestamp":1379376000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Siemens Corporation and Xoran Technologies"},{"name":"Mayo Clinic Otorhinolaryngology Research Committee"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Forum Allergy Rhinol"],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>We aimed to test the hypothesis that three\u2010dimensional (3D) volume\u2010based scoring of computed tomography (CT) images of the paranasal sinuses was superior to Lund\u2010Mackay CT scoring of disease severity in chronic rhinosinusitis (CRS). We determined correlation between changes in CT scores (using each scoring system) with changes in other measures of disease severity (symptoms, endoscopic scoring, and quality of life) in patients with CRS treated with triamcinolone.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study group comprised 48 adult subjects with CRS. Baseline symptoms and quality of life were assessed. Endoscopy and CT scans were performed. Patients received a single systemic dose of intramuscular triamcinolone and were reevaluated 1 month later. Strengths of the correlations between changes in CT scores and changes in CRS signs and symptoms and quality of life were determined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We observed some variability in degree of improvement for the different symptom, endoscopic, and quality\u2010of\u2010life parameters after treatment. Improvement of parameters was significantly correlated with improvement in CT disease score using both CT scoring methods. However, volumetric CT scoring had greater correlation with these parameters than Lund\u2010Mackay scoring.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Volumetric scoring exhibited higher degree of correlation than Lund\u2010Mackay scoring when comparing improvement in CT score with improvement in score for symptoms, endoscopic exam, and quality of life in this group of patients who received beneficial medical treatment for CRS.<\/jats:p><\/jats:sec>","DOI":"10.1002\/alr.21219","type":"journal-article","created":{"date-parts":[[2013,10,8]],"date-time":"2013-10-08T16:54:14Z","timestamp":1381251254000},"page":"963-972","source":"Crossref","is-referenced-by-count":56,"title":["Three\u2010dimensional volumetric computed tomographic scoring as an objective outcome measure for chronic rhinosinusitis: clinical correlations and comparison to Lund\u2010Mackay scoring"],"prefix":"10.1002","volume":"3","author":[{"given":"John 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Allergic Diseases Mayo Clinic  Rochester MN"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph J.","family":"Ocel","sequence":"additional","affiliation":[{"name":"Radiologists of North Iowa  Mason City IA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Tombers","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery Mayo Clinic  Rochester MN"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rizwan","family":"Siwani","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Adolescent Medicine Mayo Clinic  Rochester MN"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas M.","family":"Orme","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Diseases Mayo Clinic  Rochester MN"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kurtis 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