{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T18:25:10Z","timestamp":1748370310427},"reference-count":25,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2014,4,29]],"date-time":"2014-04-29T00:00:00Z","timestamp":1398729600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Forum Allergy Rhinol"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The effect of the type of Hymenoptera on the severity of systemic reactions (SRs) is a controversial issue. The aim of the present study was to evaluate demographic, clinical, diagnostic, and therapeutic features of moderate\u2010to\u2010severe SRs in children with venom hypersensitivity and to compare the role of the honeybee and wasp stings in these reactions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data on children with moderate\u2010to\u2010severe SRs after a Hymenoptera sting were retrospectively collected for a 17\u2010year period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 55 children with moderate\u2010to\u2010severe SRs (wasp: 44, honeybee: 11) to venom stings were included in the study. In the honeybee group, comorbid allergic rhinitis and any type of atopic disease was more frequent compared to the wasp group (<jats:italic>p<\/jats:italic> = 0.009 and <jats:italic>p<\/jats:italic> = 0.01, respectively). In 50.9% of the children, family history of SR to the same venom type was higher in the honeybee group (<jats:italic>p<\/jats:italic> = 0.02). Dyspnea was more frequent in the wasp, and cyanosis was more frequent in the honeybee compared to each other (<jats:italic>p<\/jats:italic> = 0.02 and <jats:italic>p<\/jats:italic> &lt; 0.001, respectively). Prick tests results were significantly different between the groups (<jats:italic>p<\/jats:italic> = 0.038). There was no difference between honeybee and wasp in moderate\u2010to\u2010severe SR groups in terms of seasonal tendency, age at admission, age at first SR, gender, previous history of SR, sting localization, latency, and affected organ systems (<jats:italic>p<\/jats:italic> &gt; 0.05 for each).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Moderate\u2010to\u2010severe SRs with honeybee and wasp venoms in children may differ in the severity of respiratory symptoms\/signs at presentation, in addition to comorbidity of atopic diseases and family history of the SRs.<\/jats:p><\/jats:sec>","DOI":"10.1002\/alr.21338","type":"journal-article","created":{"date-parts":[[2014,4,29]],"date-time":"2014-04-29T14:40:41Z","timestamp":1398782441000},"page":"548-554","source":"Crossref","is-referenced-by-count":3,"title":["Comparison of moderate to severe systemic reactions with honeybee and wasp in children"],"prefix":"10.1002","volume":"4","author":[{"given":"Hacer Ilbilge Ertoy","family":"Karagol","sequence":"first","affiliation":[{"name":"Department of Pediatric Asthma and Allergy Gazi University School of Medicine  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arzu","family":"Bakirtas","sequence":"additional","affiliation":[{"name":"Department of Pediatric Asthma and Allergy Gazi University School of Medicine  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ozlem","family":"Yilmaz","sequence":"additional","affiliation":[{"name":"Department of Pediatric Asthma and Allergy Gazi University School of Medicine  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erdem","family":"Topal","sequence":"additional","affiliation":[{"name":"Department of Pediatric Asthma and Allergy Gazi University School of Medicine  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mustafa","family":"Arga","sequence":"additional","affiliation":[{"name":"Department of Pediatric Asthma and Allergy Gazi University School of Medicine  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet Sad\u0131k","family":"Demirsoy","sequence":"additional","affiliation":[{"name":"Department of Pediatric Asthma and Allergy Gazi University School of Medicine  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ipek","family":"Turktas","sequence":"additional","affiliation":[{"name":"Department of Pediatric Asthma and Allergy Gazi University School of Medicine  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,4,29]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.all.0000235904.87676.40"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.2011.03788.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/cea.12144"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2007.01413.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3038.2009.00863.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3038.2010.01054.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2009.08.027"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2012.03.024"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-0546(09)71721-5"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.2009.03324.x"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2005.00963.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1081-1206(10)63203-6"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2007.01588.x"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anai.2011.09.015"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.2500\/108854194778703071"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3038.1999.00027.x"},{"key":"e_1_2_6_18_1","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1001\/archinte.1970.00310040089010","article-title":"Allergy to the Hymenoptera venom. Clinical study of 400 patients","volume":"125","author":"Brown H","year":"1970","journal-title":"Arch Intern Med"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1157\/13094024"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2011.01.025"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aller.2010.11.002"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.3109\/02770906609106941"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(77)91953-5"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2005.06.026"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3038.2011.01154.x"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOP.0b013e328361a496"}],"container-title":["International Forum of Allergy &amp; Rhinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Falr.21338","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/alr.21338","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T14:39:32Z","timestamp":1696603172000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/alr.21338"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4,29]]},"references-count":25,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2014,7]]}},"alternative-id":["10.1002\/alr.21338"],"URL":"https:\/\/doi.org\/10.1002\/alr.21338","archive":["Portico"],"relation":{},"ISSN":["2042-6976","2042-6984"],"issn-type":[{"value":"2042-6976","type":"print"},{"value":"2042-6984","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,4,29]]}}}