{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,7]],"date-time":"2023-10-07T07:43:16Z","timestamp":1696664596360},"reference-count":12,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,4,6]],"date-time":"2015-04-06T00:00:00Z","timestamp":1428278400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Forum Allergy Rhinol"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Anaphylaxis is the most serious potential complication from allergy treatment with subcutaneous immunotherapy (SCIT). Quality measures were developed with the goal to decrease the incidence of complications resulting from SCIT and improve the safety of care provided.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The incidence and characteristics of anaphylaxis episodes resulting from SCIT was measured between 2008 and 2012 prior to implementation of quality measures including vial verification, vial testing, and standardized training across 6 allergy delivery sites. Errors and anaphylaxis rates were then tracked prospectively over a 2\u2010year period after implementation of these process measures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>From 2008 to 2012 there were 9 episodes of anaphylaxis or 0.02% of injections\/year. Eight patients had sufficient information from which to derive meaningful data. Patient identification error led to anaphylaxis in 2 patients, dosing error in 2, and compounding error in 1 patient. In 2 patients, anaphylaxis occurred with advancement during pollen season, and in 1 patient no clear reason could be identified although she had asthma as a risk factor. After implementation of quality improvement measures the anaphylaxis rate fell to 0 of 8948 injections for years 2013 and 2014.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Errors in the mixing and administration of allergy serum comprised the majority of identifiable factors that led to anaphylaxis. Implementation of quality measures, including vial verification and vial testing, can improve safety and decrease anaphylaxis rates in the delivery of allergy immunotherapy.<\/jats:p><\/jats:sec>","DOI":"10.1002\/alr.21487","type":"journal-article","created":{"date-parts":[[2015,4,6]],"date-time":"2015-04-06T21:39:24Z","timestamp":1428356364000},"page":"513-516","source":"Crossref","is-referenced-by-count":2,"title":["Impact of quality improvement measures on the delivery of allergy immunotherapy: a 2\u2010year follow\u2010up"],"prefix":"10.1002","volume":"5","author":[{"given":"Jose L.","family":"Mattos","sequence":"first","affiliation":[{"name":"Department of Otolaryngology University of Pittsburgh Medical Center  Pittsburgh PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Berrylin J.","family":"Ferguson","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology University of Pittsburgh Medical Center  Pittsburgh PA USA"},{"name":"School of Medicine University of Pittsburgh  Pittsburgh PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stella","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology University of Pittsburgh Medical Center  Pittsburgh PA USA"},{"name":"School of Medicine University of Pittsburgh  Pittsburgh PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,4,6]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2010.12.1106"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2005.05.017"},{"issue":"234","key":"e_1_2_6_4_1","first-page":"1","article-title":"Summary health statistics for U.S. children: National Health Interview Survey, 2006","volume":"10","author":"Bloom B","year":"2007","journal-title":"Vital Health Stat"},{"issue":"240","key":"e_1_2_6_5_1","first-page":"1","article-title":"Summary health statistics for U.S. adults: National Health Interview Survey, 2007","volume":"10","author":"Pleis JR","year":"2009","journal-title":"Vital Health Stat"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.2500\/aap.2007.28.2934"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2008.06.003"},{"issue":"1","key":"e_1_2_6_8_1","first-page":"CD001936","article-title":"Allergen injection immunotherapy for seasonal allergic rhinitis","author":"Calderon MA","year":"2007","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(89)90355-2"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2014.01.004"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2009.10.060"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2010.09.034"},{"key":"e_1_2_6_13_1","first-page":"51","article-title":"New congressional bill attempts to aid pharmacy response to drug shortages: compounding and tracing provisions seek to improve quality of drug supply","volume":"39","author":"Barlas S.","year":"2014","journal-title":"P.T."}],"container-title":["International Forum of Allergy &amp; Rhinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Falr.21487","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/alr.21487","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T15:42:46Z","timestamp":1696606966000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/alr.21487"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4,6]]},"references-count":12,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,6]]}},"alternative-id":["10.1002\/alr.21487"],"URL":"https:\/\/doi.org\/10.1002\/alr.21487","archive":["Portico"],"relation":{},"ISSN":["2042-6976","2042-6984"],"issn-type":[{"value":"2042-6976","type":"print"},{"value":"2042-6984","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4,6]]}}}