{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T02:00:41Z","timestamp":1785463241038,"version":"3.56.0"},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,9,8]],"date-time":"2015-09-08T00:00:00Z","timestamp":1441670400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Forum Allergy Rhinol"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Odontogenic sinusitis and sinonasal complications of dental disease or treatment (SCDDT) play a relevant, often underappreciated role in paranasal sinus infections. Treating SCDDT patients requires tailored medical and surgical approaches in order to achieve acceptable success rates. These approaches differ from common rhinogenic sinusitis treatment protocols mostly because of the different etiopathogenesis. Our study comprehensively evaluated microbiology and antibiotic resistance in SCDDT patients and compared findings with a control group of patients affected by rhinogenic sinusitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed microbiological sampling during surgery on 28 patients with SCDDT and 16 patients with chronic rhinosinusitis with nasal polyps (CRSwNP). Colonies were isolated, Gram\u2010stained, and the species identified using classic biochemical methods. These results were confirmed by DNA pyrosequencing, and then the resistance profile of each SCDDT isolate to various antibiotics was tested.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Microbial growth was observed in all SCDDT patients, whereas samples from 60% of patients in the control group failed to yield any bacterial growth (<jats:italic>p<\/jats:italic> &lt; 0.001). Anaerobes grew in 14% of SCDDT patients as compared to 7% of CRSwNP patients (<jats:italic>p<\/jats:italic> = 0.42). Of the isolates from SCDDT patients, 70% were susceptible to amoxicillin\/clavulanate, whereas all isolates were susceptible to levofloxacin, teicoplanin, and vancomycin. Of the staphylococci identified, 80% were capable of producing beta\u2010lactamase.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Given the extent of microbiological contamination within the maxillary sinus of SCDDT patients, these infections should be regarded as a different class of conditions from rhinogenic sinusitis. Our findings support the need for different approaches in the treatment of SCDDT patients.<\/jats:p><\/jats:sec>","DOI":"10.1002\/alr.21629","type":"journal-article","created":{"date-parts":[[2015,9,8]],"date-time":"2015-09-08T08:31:54Z","timestamp":1441701114000},"page":"41-45","source":"Crossref","is-referenced-by-count":86,"title":["Odontogenic and rhinogenic chronic sinusitis: a modern microbiological comparison"],"prefix":"10.1002","volume":"6","author":[{"given":"Alberto Maria","family":"Saibene","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck San Paolo Hospital University of Milan  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Vassena","sequence":"additional","affiliation":[{"name":"Laboratory of Clinical Chemistry and Microbiology National Institute for Research and Treatment (IRCCS) Galeazzi Orthopaedic Institute  Milan 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