{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T20:07:02Z","timestamp":1778616422244,"version":"3.51.4"},"reference-count":23,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,11,17]],"date-time":"2015-11-17T00:00:00Z","timestamp":1447718400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Forum Allergy Rhinol"],"published-print":{"date-parts":[[2016,3]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The incidence and potential disease impact of paranasal sinus anatomic variants in patients with recurrent acute rhinosinusitis (RARS) has important implications for management, including surgery, but is incompletely defined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective review of 26 patients with RARS who had undergone computed tomography (CT) was performed. Patient demographics, RARS severity and comorbidities were reviewed. CT scans were reviewed for the incidence of anatomic variants in all patients. The pattern of inflammatory changes was explored in the subset of patients with acute rhinosinusitis at the time of CT. Potential correlation between the presence of anatomic variants and disease severity were investigated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the patient cohort who met inclusion criteria, the most common variants included agger nasi cell (88.5%), concha bullosa (53.8%), infraorbital cell (50%), and deviated nasal septum with middle meatus obstruction (42%). In exploring correlations with RARS severity, type 2 frontal cells correlated with a greater number of years with RARS (0.0363). In the 23 patients who underwent CT at the time of an acute infection, no statistically significant correlation was found between severity or location of inflammatory changes and the presence of anatomic variants.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study describes the incidence of anatomic variants in a cohort of patients with RARS. A correlation between the presence of anatomic variants and the pattern of inflammatory changes was not identified.<\/jats:p><\/jats:sec>","DOI":"10.1002\/alr.21658","type":"journal-article","created":{"date-parts":[[2015,11,17]],"date-time":"2015-11-17T13:56:48Z","timestamp":1447768608000},"page":"328-333","source":"Crossref","is-referenced-by-count":22,"title":["Anatomic variants of the paranasal sinuses in patients with recurrent acute rhinosinusitis"],"prefix":"10.1002","volume":"6","author":[{"given":"Patricia Anne","family":"Loftus","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Albert Einstein College of Medicine  Bronx NY"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Population Health Division of Biostatistics, Albert Einstein College of Medicine  Bronx NY"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abtin","family":"Tabaee","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Weill Cornell Medical College  New York NY"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,11,17]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599811426089"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2007.06.726"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000154738.40690.dd"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.20804"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/019459989010300516"},{"key":"e_1_2_6_7_1","first-page":"183","article-title":"Staging in rhinosinusitus","volume":"31","author":"Lund VJ","year":"1993","journal-title":"Rhinology"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2007.02.002"},{"key":"e_1_2_6_9_1","first-page":"191","article-title":"The prevalence of anatomical variations in osteomeatal unit in patients with chronic rhinosinusitis","volume":"66","author":"Azila A","year":"2011","journal-title":"Med J Malaysia"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199101000-00010"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ca.20507"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.5152\/eajm.2013.23"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2003.08.012"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2004.04.012"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215115000821"},{"key":"e_1_2_6_16_1","first-page":"612","article-title":"The incidence of nasal septal deviation and its relation with chronic rhinosinusitis in patients undergoing functional endoscopic sinus surgery","volume":"65","author":"Madani SA","year":"2015","journal-title":"J Pak Med Assoc"},{"key":"e_1_2_6_17_1","first-page":"117","article-title":"Nasal septal deformities in chronic rhinosinusitis patients: clinical and radiological aspects","volume":"34","author":"Poje G","year":"2014","journal-title":"Acta Otorhinolaryngol Ital"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.14.13762"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004728-198809010-00012"},{"key":"e_1_2_6_20_1","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1007\/BF02996431","article-title":"Concha bullosa: frequency and appearances on sinonasal CT","volume":"52","author":"Maru YK","year":"1999","journal-title":"Indian J Otolaryngol Head Neck Surg"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0385-8146(98)00024-8"},{"key":"e_1_2_6_22_1","first-page":"763","article-title":"Anatomical variations of the lateral nasal wall and paranasal sinuses: a CT study for endoscopic sinus surgery (ESS) in Thai patients","volume":"88","author":"Nitinavakarn B","year":"2005","journal-title":"J Med Assoc Thai"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2012.26.3774"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00276-000-0243-8"}],"container-title":["International Forum of Allergy &amp; 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