{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T15:00:41Z","timestamp":1785164441794,"version":"3.55.0"},"reference-count":19,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,2,19]],"date-time":"2016-02-19T00:00:00Z","timestamp":1455840000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"S\u00e3o Paulo Research Foundation (FAPESP)","award":["FAPESP 2013\/21944-7"],"award-info":[{"award-number":["FAPESP 2013\/21944-7"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Forum Allergy Rhinol"],"published-print":{"date-parts":[[2016,5]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Our goals were to assess whether allergic rhinitis (AR) is an aggravating factor that affects the severity of sleep apnea in children with tonsils\/adenoid hypertrophy (T&amp;A) and to compare polysomnographic data from children with and without AR.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This prospective study included 135 children (age range, 3 to 14 years) with sleep\u2010disordered breathing (SDB) resulting from T&amp;A. Children with lung, neurological, or craniofacial problems; septal deviations; previous pharyngeal surgeries; or orthodontic treatments were excluded. All children underwent a clinical evaluation, nasopharyngoscopy or lateral X\u2010ray imaging, sleep study, and hypersensitivity skin\u2010prick test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean patient age was 6.44 \u00b1 2.55 years (83 males). AR was present in 42.2% of the children; 40% presented with sleep apnea; and 17.04% had sleep apnea and AR. The percentage of time spent in the rapid eye movement (REM) sleep stage was lower among children with AR without sleep apnea (<jats:italic>p<\/jats:italic> = 0.028); however, the percentage of REM sleep was not significantly different among children with apnea (<jats:italic>p<\/jats:italic> = 0.2922). No difference in the apnea\u2010hypopnea index (AHI) was observed between the children with (AHI = 2.79 events\/hour) and without AR (3.75 events\/hour, <jats:italic>p<\/jats:italic> = 0.4427). A multivariate analysis showed that nasal congestion was an important factor that can affect the duration of the REM sleep stage.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>AR affects REM sleep in children with SDB without sleep apnea, and AR is not an aggravating factor regarding the severity of AHI.<\/jats:p><\/jats:sec>","DOI":"10.1002\/alr.21689","type":"journal-article","created":{"date-parts":[[2016,2,20]],"date-time":"2016-02-20T14:41:33Z","timestamp":1455979293000},"page":"465-471","source":"Crossref","is-referenced-by-count":22,"title":["Allergic rhinitis affects the duration of rapid eye movement sleep in children with sleep\u2010disordered breathing without sleep apnea"],"prefix":"10.1002","volume":"6","author":[{"given":"Renata C.","family":"Di Francesco","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Alvarez","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,2,19]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOO.0b013e32835ff132"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2431-12-175"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.21529"},{"key":"e_1_2_7_5_1","unstructured":"WHO Multicentre Growth Reference Study Group.WHO Child Growth Standards: length\/height\u2010for\u2010age weight\u2010for\u2010age weight\u2010for\u2010length weight\u2010for\u2010height and body mass index\u2010for\u2010age: methods and development.Geneva:World Health Organization;2006.http:\/\/www.who.int\/childgrowth\/standards\/technical_report\/en\/. 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