{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T18:08:31Z","timestamp":1740161311082,"version":"3.37.3"},"reference-count":31,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100002583","name":"Gyeongsang National University Hospital","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100002583","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Institute of Health Sciences","award":["GNU-2013-02"],"award-info":[{"award-number":["GNU-2013-02"]}]},{"name":"Korean Health Technology R&D Project"},{"DOI":"10.13039\/501100003625","name":"Ministry of Health and Welfare","doi-asserted-by":"publisher","award":["HI13C13590000"],"award-info":[{"award-number":["HI13C13590000"]}],"id":[{"id":"10.13039\/501100003625","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Forum Allergy Rhinol."],"published-print":{"date-parts":[[2016,10]]},"DOI":"10.1002\/alr.21786","type":"journal-article","created":{"date-parts":[[2016,4,28]],"date-time":"2016-04-28T06:33:55Z","timestamp":1461825235000},"page":"1007-1012","source":"Crossref","is-referenced-by-count":2,"title":["Interleukin-4 enzyme-linked immunospot assay may be useful for diagnosing sensitization to house dust mite"],"prefix":"10.1002","volume":"6","author":[{"given":"Dong-Yeop","family":"Chang","sequence":"first","affiliation":[{"name":"Institute of Health Sciences; Gyeongsang National University; Jinju Republic of Korea"},{"name":"Department of Otorhinolaryngology; Gyeongsang National University Hospital; Jinju Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jino","family":"Lee","sequence":"additional","affiliation":[{"name":"Laboratory of Immunology and Infectious Diseases; Graduate School of Medical Science and Engineering; KAIST Daejeon Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung-Won","family":"Choi","sequence":"additional","affiliation":[{"name":"Laboratory of Immunology and Infectious Diseases; Graduate School of Medical Science and Engineering; KAIST Daejeon Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyeong Joo","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology; Gyeongsang National University Hospital; Jinju Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyunmo","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology; Gyeongsang National University Hospital; Jinju Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seong Chul","family":"Yeo","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology; Gyeongsang National University Hospital; Jinju Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yeon-Hee","family":"Joo","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology; Gyeongsang National University Hospital; Jinju Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyun-Jin","family":"Cho","sequence":"additional","affiliation":[{"name":"Institute of Health Sciences; Gyeongsang National University; Jinju Republic of Korea"},{"name":"Department of Otorhinolaryngology; Gyeongsang National University Hospital; Jinju Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sea-Yuong","family":"Jeon","sequence":"additional","affiliation":[{"name":"Institute of Health Sciences; Gyeongsang National University; Jinju Republic of Korea"},{"name":"Department of Otorhinolaryngology; Gyeongsang National University Hospital; Jinju Republic of Korea"},{"name":"Department of Otorhinolaryngology; Gyeongsang National University School of Medicine; Jinju Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rock Bum","family":"Kim","sequence":"additional","affiliation":[{"name":"Regional Cardiocerebrovascular Disease Center; Gyeongsang National University Hospital; Jinju Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang-Wook","family":"Kim","sequence":"additional","affiliation":[{"name":"Institute of Health Sciences; Gyeongsang National University; Jinju Republic of Korea"},{"name":"Department of Otorhinolaryngology; Gyeongsang National University Hospital; Jinju Republic of Korea"},{"name":"Department of Otorhinolaryngology; Gyeongsang National University School of Medicine; Jinju Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,4,28]]},"reference":[{"key":"10.1002\/alr.21786-BIB0001|alr21786-cit-0002","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1258\/0007142001903481","article-title":"Overview of \u2018allergy and allergic diseases: with a view to the future","volume":"56","author":"Kay","year":"2000","journal-title":"Br Med Bull"},{"key":"10.1002\/alr.21786-BIB0002|alr21786-cit-0003","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.jaci.2004.06.046","article-title":"In vitro assays for the diagnosis of IgE-mediated disorders","volume":"114","author":"Hamilton","year":"2004","journal-title":"J Allergy Clin Immunol"},{"issue":"Suppl 1","key":"10.1002\/alr.21786-BIB0003|alr21786-cit-0004","doi-asserted-by":"crossref","first-page":"S6","DOI":"10.2500\/aap.2012.33.3532","article-title":"Chapter 2: skin testing in allergy","volume":"33","author":"Carr","year":"2012","journal-title":"Allergy Asthma Proc"},{"key":"10.1002\/alr.21786-BIB0004|alr21786-cit-0005","first-page":"20","article-title":"Correlation between skin prick test and MAST-immunoblot results in patients with chronic rhinitis","volume":"31","author":"Kim","year":"2013","journal-title":"Asian Pac J Allergy Immunol"},{"key":"10.1002\/alr.21786-BIB0005|alr21786-cit-0006","first-page":"329","article-title":"Comparison of three in vitro assays for serum IgE with skin testing in asthmatic children","volume":"73","author":"Kam","year":"1994","journal-title":"Ann Allergy"},{"key":"10.1002\/alr.21786-BIB0006|alr21786-cit-0007","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1111\/j.1398-9995.1990.tb01080.x","article-title":"Evaluation of a capsulated hydrophilic carrier polymer (the ImmunoCAP) for measurement of specific IgE antibodies","volume":"45","author":"Ewan","year":"1990","journal-title":"Allergy"},{"key":"10.1002\/alr.21786-BIB0007|alr21786-cit-0008","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1111\/j.1365-2222.1996.tb00596.x","article-title":"A clinical evaluation in children of the Pharmacia ImmunoCAP system for inhalant allergens","volume":"26","author":"Gleeson","year":"1996","journal-title":"Clin Exp Allergy"},{"key":"10.1002\/alr.21786-BIB0008|alr21786-cit-0009","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1515\/CCLM.2000.040","article-title":"The clinical usefulness of the measurement of cytokines","volume":"38","author":"Bienvenu","year":"2000","journal-title":"Clin Chem Lab Med"},{"key":"10.1002\/alr.21786-BIB0009|alr21786-cit-0010","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1164\/ajrccm.163.4.2009100","article-title":"Rapid detection of Mycobacterium tuberculosis infection by enumeration of antigen-specific T cells","volume":"163","author":"Lalvani","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1002\/alr.21786-BIB0010|alr21786-cit-0011","doi-asserted-by":"crossref","first-page":"2285","DOI":"10.1097\/00002030-200211220-00008","article-title":"Rapid detection of active and latent tuberculosis infection in HIV-positive individuals by enumeration of Mycobacterium tuberculosis-specific T cells","volume":"16","author":"Chapman","year":"2002","journal-title":"AIDS"},{"key":"10.1002\/alr.21786-BIB0011|alr21786-cit-0012","doi-asserted-by":"crossref","first-page":"3853","DOI":"10.4049\/jimmunol.151.7.3853","article-title":"Immunolocalization of cytokines in the nasal mucosa of normal and perennial rhinitic subjects. The mast cell as a source of IL-4, IL-5, and IL-6 in human allergic mucosal inflammation","volume":"151","author":"Bradding","year":"1993","journal-title":"J Immunol"},{"key":"10.1002\/alr.21786-BIB0012|alr21786-cit-0013","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1046\/j.1365-3083.1998.00278.x","article-title":"Ten-year follow-up study of allergen-specific immunoglobulin E and immunoglobulin G4, soluble interleukin-2 receptor, interleukin-4, soluble intercellular adhesion molecule-1 and soluble vascular cell adhesion molecule-1 in serum of patients on immunotherapy for perennial allergic rhinitis","volume":"47","author":"Ohashi","year":"1998","journal-title":"Scand J Immunol"},{"key":"10.1002\/alr.21786-BIB0013|alr21786-cit-0014","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1046\/j.1365-2222.1997.560878.x","article-title":"Specific induction of interleukin-4-producing cells in response to in vitro allergen stimulation in atopic individuals","volume":"27","author":"Gabrielsson","year":"1997","journal-title":"Clin Exp Allergy"},{"key":"10.1002\/alr.21786-BIB0014|alr21786-cit-0015","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1111\/j.1365-2222.1995.tb01088.x","article-title":"Interleukin-4 and interferon-gamma production in atopic and non-atopic children with asthma","volume":"25","author":"Tang","year":"1995","journal-title":"Clin Exp Allergy"},{"key":"10.1002\/alr.21786-BIB0015|alr21786-cit-0016","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/0022-1759(83)90308-3","article-title":"A solid-phase enzyme-linked immunospot (ELISPOT) assay for enumeration of specific antibody-secreting cells","volume":"65","author":"Czerkinsky","year":"1983","journal-title":"J Immunol Methods"},{"key":"10.1002\/alr.21786-BIB0016|alr21786-cit-0017","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/0022-1759(88)90306-7","article-title":"A novel two colour ELISPOT assay. I. Simultaneous detection of distinct types of antibody-secreting cells","volume":"115","author":"Czerkinsky","year":"1988","journal-title":"J Immunol Methods"},{"key":"10.1002\/alr.21786-BIB0017|alr21786-cit-0018","first-page":"259","article-title":"Direct comparison of ELISPOT and ELISA-based assays for detection of individual cytokine-secreting cells","volume":"13","author":"Tanguay","year":"1994","journal-title":"Lymphokine Cytokine Res"},{"key":"10.1002\/alr.21786-BIB0018|alr21786-cit-0019","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S0022-1759(01)00520-8","article-title":"Detection of spontaneous and antigen-induced human interleukin-4 responses in vitro: comparison of ELISPOT, a novel ELISA and real-time RT-PCR","volume":"260","author":"Ekerfelt","year":"2002","journal-title":"J Immunol Methods"},{"key":"10.1002\/alr.21786-BIB0019|alr21786-cit-0020","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1080\/08820130802083648","article-title":"ELISpot displays a better detection over ELISA of T helper (Th) 2-type cytokine-production by ex vivo-stimulated antigen-specific T cells from human peripheral blood","volume":"37","author":"Minang","year":"2008","journal-title":"Immunol Invest"},{"key":"10.1002\/alr.21786-BIB0020|alr21786-cit-0021","first-page":"15","article-title":"Chemistry and biology of the ELISPOT assay","volume":"302","author":"Kalyuzhny","year":"2005","journal-title":"Methods Mol Biol"},{"key":"10.1002\/alr.21786-BIB0021|alr21786-cit-0022","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.5588\/ijtld.10.0631","article-title":"Interferon-gamma release assays and childhood tuberculosis: systematic review and meta-analysis","volume":"15","author":"Mandalakas","year":"2011","journal-title":"Int J Tuberc Lung Dis"},{"key":"10.1002\/alr.21786-BIB0022|alr21786-cit-0023","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1006\/clin.1994.1076","article-title":"Decreased frequency of functional natural interferon-producing cells in peripheral blood of patients with the acquired immune deficiency syndrome","volume":"71","author":"Howell","year":"1994","journal-title":"Clin Immunol Immunopathol"},{"key":"10.1002\/alr.21786-BIB0023|alr21786-cit-0024","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1002\/(SICI)1097-0215(19970611)71:6<932::AID-IJC3>3.0.CO;2-Z","article-title":"Analysis of the T cell response to tumor and viral peptide antigens by an IFNgamma-ELISPOT assay","volume":"71","author":"Scheibenbogen","year":"1997","journal-title":"Int J Cancer"},{"key":"10.1002\/alr.21786-BIB0024|alr21786-cit-0025","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1046\/j.1365-2222.2002.01548.x","article-title":"Increased aeroallergen-specific interleukin-4-producing T cells in asthmatic adults","volume":"32","author":"Pala","year":"2002","journal-title":"Clin Exp Allergy"},{"key":"10.1002\/alr.21786-BIB0025|alr21786-cit-0026","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1111\/j.1365-2222.2007.02898.x","article-title":"Seasonal changes in antigen-specific T-helper clone sizes in patients with Japanese cedar pollinosis: a 2-year study","volume":"38","author":"Horiguchi","year":"2008","journal-title":"Clin Exp Allergy"},{"key":"10.1002\/alr.21786-BIB0026|alr21786-cit-0027","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S0022-1759(01)00451-3","article-title":"A simple method to reduce the background and improve well-to-well reproducibility of staining in ELISPOT assays","volume":"257","author":"Kalyuzhny","year":"2001","journal-title":"J Immunol Methods"},{"key":"10.1002\/alr.21786-BIB0027|alr21786-cit-0028","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1159\/000107464","article-title":"House dust and storage mite extracts influence skin keratinocyte and fibroblast function","volume":"145","author":"Arlian","year":"2008","journal-title":"Int Arch Allergy Immunol"},{"key":"10.1002\/alr.21786-BIB0028|alr21786-cit-0029","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1007\/s10493-013-9703-9","article-title":"Proteins and endotoxin in house dust mite extracts modulate cytokine secretion and gene expression by dermal fibroblasts","volume":"61","author":"Rockwood","year":"2013","journal-title":"Exp Appl Acarol"},{"key":"10.1002\/alr.21786-BIB0029|alr21786-cit-0030","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/S0091-6749(99)70292-7","article-title":"Frequency and characterization of antigen-specific IL-4- and IL-13-producing basophils and T cells in peripheral blood of healthy and asthmatic subjects","volume":"104","author":"Devouassoux","year":"1999","journal-title":"J Allergy Clin Immunol"},{"key":"10.1002\/alr.21786-BIB0030|alr21786-cit-0031","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1189\/jlb.68.1.125","article-title":"IL-4 production by human polymorphonuclear neutrophils","volume":"68","author":"Brandt","year":"2000","journal-title":"J Leukoc Biol"},{"key":"10.1002\/alr.21786-BIB0031|alr21786-cit-0032","doi-asserted-by":"crossref","first-page":"697","DOI":"10.3346\/jkms.2001.16.6.697","article-title":"Multicenter study on the prevalence of perennial allergic rhinitis and allergy-associated disorders","volume":"16","author":"Min","year":"2001","journal-title":"J Korean Med Sci"}],"container-title":["International Forum of Allergy &amp; Rhinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Falr.21786","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/alr.21786","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,17]],"date-time":"2023-08-17T20:18:50Z","timestamp":1692303530000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/alr.21786"}},"subtitle":["IL-4 ELISpot assay for sensitization to HDM"],"short-title":[],"issued":{"date-parts":[[2016,4,28]]},"references-count":31,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2016,10]]}},"URL":"https:\/\/doi.org\/10.1002\/alr.21786","archive":["Portico"],"relation":{},"ISSN":["2042-6976"],"issn-type":[{"type":"print","value":"2042-6976"}],"subject":[],"published":{"date-parts":[[2016,4,28]]}}}