{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T02:43:56Z","timestamp":1787798636602,"version":"build-2784847793"},"reference-count":21,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2017,5,11]],"date-time":"2017-05-11T00:00:00Z","timestamp":1494460800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Forum Allergy Rhinol"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Episodic or recurrent sinonasal symptoms are often suspected as \u201csinus\u201d in origin. With normal sinus radiology between events, the diagnosis of recurrent acute rhinosinusitis (RecARS) is made. However, other conditions can produce episodic symptoms. In this study we analyze acutely performed computed tomography (CT) in a population with suspected or self\u2010diagnosed \u201csinus\u201d disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients referred to a tertiary clinic for suspected RecARS were assessed. Sinus changes were defined by CT (initial assessment) and during the acute event, by a semiurgent CT performed during the symptomatic episode. Mucosal thickening, ostiomeatal compromise, and severe septal deformity were recorded. Symptom profile was assessed during both time\u2010points with the 22\u2010item Sino\u2010Nasal Outcome Test (SNOT\u201022).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty\u2010eight patients (49.5 \u00b1 14.7 years of age, 70.8% female) were assessed. At presentation, 75% were resolute in a diagnosis of \u201csinus.\u201d Baseline Lund\u2010Mackay scores were &lt;6 (median 0 [interquartile range 1]). Ostiomeatal compromise was 6.8% left and 4.5% right at baseline. Of the patients who returned for acute CT (n = 27), SNOT\u201022 and subdomains were similar to baseline. Septal deviation was similar (13.6% vs 15.3%). Acutely, ostiomeatal compromise was 0% left and 7.4% right (n = 2). Of these 2 patients with ostiomeatal compromise, 1 was diagnosed with RecARS (4%) and the other with triptan\u2010responsive migraine, with incidental sinus changes. Final diagnosis was rhinitis (47%), headache\/migraine (37%), and facial pain otherwise undefined (12.5%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Patients with a history of \"recurrent acute sinusitis\" and normal CT scans between episodes rarely have abnormal CT findings during acute exacerbations of symptoms. Antibiotics and surgical intervention are often inappropriate in this population.<\/jats:p><\/jats:sec>","DOI":"10.1002\/alr.21925","type":"journal-article","created":{"date-parts":[[2017,5,11]],"date-time":"2017-05-11T20:25:38Z","timestamp":1494534338000},"page":"726-733","source":"Crossref","is-referenced-by-count":24,"title":["Acute radiology rarely confirms sinus disease in suspected recurrent acute rhinosinusitis"],"prefix":"10.1002","volume":"7","author":[{"given":"Henry P.","family":"Barham","sequence":"first","affiliation":[{"name":"Sinus and Nasal Specialists of Louisiana  Baton Rouge LA"},{"name":"Rhinology and Skull Base Research Group, St. Vincent's Centre for Applied Medical Research University of New South Wales  Sydney NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander S.","family":"Zhang","sequence":"additional","affiliation":[{"name":"Rhinology and Skull Base Research Group, St. Vincent's Centre for Applied Medical Research University of New South Wales  Sydney NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenna M.","family":"Christensen","sequence":"additional","affiliation":[{"name":"Rhinology and Skull Base Research Group, St. Vincent's Centre for Applied Medical Research University of New South Wales  Sydney NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymond","family":"Sacks","sequence":"additional","affiliation":[{"name":"Rhinology and Skull Base Research Group, St. Vincent's Centre for Applied Medical Research University of New South Wales  Sydney NSW Australia"},{"name":"Australian School of Advanced Medicine Macquarie University  Sydney NSW Australia"},{"name":"Department of Otolaryngology University of Sydney  Sydney NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard J.","family":"Harvey","sequence":"additional","affiliation":[{"name":"Rhinology and Skull Base Research Group, St. Vincent's Centre for Applied Medical Research University of New South Wales  Sydney NSW Australia"},{"name":"Australian School of Advanced Medicine Macquarie University  Sydney NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,5,11]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599811426089"},{"key":"e_1_2_6_3_1","first-page":"1","article-title":"European Position Paper on Rhinosinusitis and Nasal Polyps 2012","volume":"3","author":"Fokkens WJ","year":"2012","journal-title":"Rhinol Suppl"},{"key":"e_1_2_6_4_1","first-page":"S1","article-title":"Clinical practice guideline (update): adult sinusitis","volume":"152","author":"Rosenfeld RM","year":"2015","journal-title":"Otolaryngol Head Neck Surg"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599813505841"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599813503791"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.2500\/ajr.2008.22.3177"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.21533"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2001.119324"},{"key":"e_1_2_6_10_1","first-page":"1","article-title":"European Position Paper on Rhinosinuisitis and Nasal Polyps 2007","volume":"20","author":"Fokkens WJ","year":"2007","journal-title":"Rhinol Suppl"},{"key":"e_1_2_6_11_1","first-page":"183","article-title":"Staging in rhinosinusitis","volume":"31","author":"Lund VJ MI.","year":"1993","journal-title":"Rhinology"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-4486.2009.01995.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102413485658"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/145.6.849"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.21546"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dki339"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.inf.0000164706.91337.5d"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1006\/abbi.1995.1086"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(62)90321-1"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016488409107569"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/157.1.133"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.20084"}],"container-title":["International Forum of Allergy &amp; 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