{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T23:20:47Z","timestamp":1792797647002,"version":"4.5.0"},"reference-count":28,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2017,7,28]],"date-time":"2017-07-28T00:00:00Z","timestamp":1501200000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Forum Allergy Rhinol"],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Patient\u2010reported control of chronic rhinosinusitis (CRS) symptoms is associated with the quality of life impact of CRS. We sought to determine if 22\u2010item Sino\u2010Nasal Outcome Test (SNOT\u201022) score is predictive of patient\u2010perceived CRS symptom control.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Prospective cross\u2010sectional study of 202 patients with CRS. Participants were asked to rate their CRS symptom control as \u201cnot at all,\u201d \u201ca little,\u201d \u201csomewhat,\u201d \u201cvery,\u201d and \u201ccompletely.\u201d The severity of patient CRS symptomatology was measured using the SNOT\u201022. The relationship between SNOT\u201022 score and patient\u2010reported CRS symptom control was determined using regression, analysis of variance (ANOVA), and receiver operating characteristic (ROC) curve analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>SNOT\u201022 was negatively associated with patient\u2010reported CRS symptom control (adjusted \u03b2 = \u22120.03; 95% CI, \u22120.04 to \u22120.02; <jats:italic>p<\/jats:italic> &lt; 0.001), after controlling for demographic and clinical characteristics. There was a significant difference in SNOT\u201022 scores of participants reporting each level of symptom control (<jats:italic>p<\/jats:italic> &lt; 0.001) with the greatest differences between participants who rated their CRS symptom control as \u201cnot at all,\u201d \u201ca little,\u201d and \u201csomewhat,\u201d which we deem poor CRS symptom control, and the group who described their level of CRS symptom control described as \u201cvery\u201d and \u201ccompletely,\u201d which we deem well\u2010controlled CRS symptoms. These results were true across all SNOT\u201022 subdomains scores as well. Using ROC analysis, a SNOT\u201022 score of 35 identified patients reporting poor vs well\u2010controlled CRS symptom control with 71.4% sensitivity and 85.5% specificity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>SNOT\u201022 score is associated with how well patients feel their CRS symptomatology is controlled. Moreover, SNOT\u201022 score can be used to accurately distinguish patients with poor vs well\u2010controlled CRS symptoms.<\/jats:p><\/jats:sec>","DOI":"10.1002\/alr.21992","type":"journal-article","created":{"date-parts":[[2017,7,28]],"date-time":"2017-07-28T16:12:39Z","timestamp":1501258359000},"page":"945-951","source":"Crossref","is-referenced-by-count":45,"title":["The 22\u2010item Sino\u2010Nasal Outcome Test accurately reflects patient\u2010reported control of chronic rhinosinusitis symptomatology"],"prefix":"10.1002","volume":"7","author":[{"given":"Stacey T.","family":"Gray","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Harvard Medical School  Boston MA"},{"name":"Department of Otolaryngology Massachusetts Eye and Ear Infirmary  Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katie M.","family":"Phillips","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Harvard Medical School  Boston MA"},{"name":"Department of Otolaryngology Massachusetts Eye and Ear Infirmary  Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lloyd P.","family":"Hoehle","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Harvard Medical School  Boston MA"},{"name":"Department of Otolaryngology Massachusetts Eye and Ear Infirmary  Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David S.","family":"Caradonna","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Harvard Medical School  Boston MA"},{"name":"Division of Otolaryngology Beth Israel Deaconess Medical Center  Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad R.","family":"Sedaghat","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Harvard Medical School  Boston MA"},{"name":"Department of Otolaryngology Massachusetts Eye and Ear Infirmary  Boston MA"},{"name":"Division of Otolaryngology Beth Israel Deaconess Medical Center  Boston MA"},{"name":"Department of Otolaryngology and Communications Enhancement Boston Children's Hospital  Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,7,28]]},"reference":[{"issue":"23","key":"e_1_2_7_2_1","first-page":"1","article-title":"European Position Paper on Rhinosinusitis and Nasal Polyps 2012","author":"Fokkens WJ","year":"2012","journal-title":"Rhinol Suppl"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2016.30.4297"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.4193\/Rhino16.211"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599815574247"},{"key":"e_1_2_7_6_1","first-page":"S209","article-title":"International consensus statement on allergy and rhinology: rhinosinusitis","volume":"6","author":"Orlandi RR","year":"2016","journal-title":"Int Forum Allergy 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