{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T19:54:57Z","timestamp":1788897297409,"version":"build-2803163510"},"reference-count":20,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2017,8,31]],"date-time":"2017-08-31T00:00:00Z","timestamp":1504137600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002641","name":"Konkuk University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002641","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Forum Allergy Rhinol"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Use of absorbable packing materials after functional endoscopic sinus surgery (FESS) is associated with increased patient comfort and a lack of need for packing removal. Different materials may induce different patterns of mucosal healing and hemostasis. This study investigated the effect of fibrin sealant (FS; Tisseel) or biodegradable synthetic polyurethane foam (Nasopore<jats:sup>\u00ae<\/jats:sup>) packing on hemostasis and wound healing after FESS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This prospective randomized controlled trial included 35 consecutive patients who underwent bilateral FESS for chronic rhinosinusitis. The patients were randomized to receive FS through aerosol spraying on 1 side and Nasopore packing on the opposite side. They were followed at 1, 2, 4, 8, and 12 weeks after surgery. Endoscopically visible packing material, crusting, adhesion, bleeding, granulation tissue formation, frontal sinus patency, and adverse effects were assessed. Subjective symptoms related to nasal packing were evaluated by using questionnaires quantified with a visual analogue scale.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>No significant differences were found between the FS\u2010treated side and the Nasopore\u2010packed side with respect to postoperative bleeding, adhesion, or frontal sinus patency. However, crusting and granulation were significantly lower in FS\u2010treated nostrils (<jats:italic>p<\/jats:italic> &lt; 0.01). The patients\u2019 satisfaction and willingness to reuse the material were not significantly different between FS and Nasopore. There were no allergic reactions to either material.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>FS and Nasopore were equally successful in achieving hemostasis and patient satisfaction after FESS. However, our results suggest that differential mucosal healing patterns may be induced by alternative absorbable hemostatic materials. FS\u2010treated sides showed more optimal healing patterns than Nasopore\u2010packed sides.<\/jats:p><\/jats:sec>","DOI":"10.1002\/alr.22011","type":"journal-article","created":{"date-parts":[[2017,8,31]],"date-time":"2017-08-31T16:46:43Z","timestamp":1504198003000},"page":"1089-1094","source":"Crossref","is-referenced-by-count":12,"title":["Comparison of the effect of aerosolized fibrin sealant and biodegradable synthetic polyurethane foam on hemostasis and wound healing after endoscopic sinus surgery: a prospective randomized study"],"prefix":"10.1002","volume":"7","author":[{"given":"Moon Sik","family":"Jung","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology Konkuk University School of Medicine  Chungju South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang Hwan","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Konkuk University School of Medicine  Chungju South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myeong Sang","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Konkuk University School of Medicine  Chungju South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,8,31]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"1","article-title":"European Position Paper on Rhinosinusitis and Nasal Polyps","author":"Fokkens WJ","year":"2012","journal-title":"Rhinol Suppl"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200409000-00007"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-009-0978-8"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2008.09.012"},{"key":"e_1_2_6_6_1","first-page":"241","article-title":"Double\u2010blind randomised controlled trial comparing Merocel with Rapid Rhino nasal packs after routine nasal surgery","volume":"41","author":"Arya AK","year":"2003","journal-title":"Rhinology"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-4486.2007.01517.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0b013e31826b8247"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcma.2010.09.001"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/194589240602000102"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0093959"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/194589240501900304"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/194589240301700405"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(01)00770-X"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2014.28.4047"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2010.24.3422"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2011.25.3600"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-008-0841-3"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjorl.2016.01.001"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2017.01.006"},{"key":"e_1_2_6_21_1","first-page":"1","article-title":"Comprehensive review on endonasal endoscopic sinus surgery","volume":"14","author":"Weber RK","year":"2015","journal-title":"GMS Curr Top Otorhinolaryngol Head Neck Surg"}],"container-title":["International Forum of Allergy &amp; Rhinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Falr.22011","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/alr.22011","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,30]],"date-time":"2023-09-30T01:15:37Z","timestamp":1696036537000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/alr.22011"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,31]]},"references-count":20,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["10.1002\/alr.22011"],"URL":"https:\/\/doi.org\/10.1002\/alr.22011","archive":["Portico"],"relation":{},"ISSN":["2042-6976","2042-6984"],"issn-type":[{"value":"2042-6976","type":"print"},{"value":"2042-6984","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8,31]]}}}