{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T23:12:31Z","timestamp":1787613151000,"version":"build-2736575974"},"reference-count":31,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,12,6]],"date-time":"2017-12-06T00:00:00Z","timestamp":1512518400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Forum Allergy Rhinol"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The use of endoscopic resection as an alternative to open surgery for sinonasal malignancies has increased in the past 20 years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The National Cancer Database was queried for cases of sinonasal squamous cell carcinoma (SNSCC) without cervical or distant metastases that were treated surgically between 2010 and 2014. They were split into 2 groups based on surgical approach: open or endoscopic. Demographics, facility and insurance type, stage, tumor characteristics, postoperative treatment, 30\u2010day readmission rate, 30\u2010 and 90\u2010day mortality, and overall survival (OS) were compared between the 2 groups. Cox proportional hazard analysis was performed. Propensity score matching (PSM) was used to mimic a randomized, controlled trial.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 1,483 patients were identified: 353 (23.8%) received endoscopic and 1130 (76.2%) received open surgery. Age, gender, race, geographic region, tumor size, surgical margins, postoperative chemoradiation, and 30\u2010day readmissions did not vary significantly between the 2 groups. Open surgery was more common in academic centers (62.8% vs 54.2%; <jats:italic>p<\/jats:italic> = 0.004), less common for tumors of the ethmoid and sphenoid sinus (<jats:italic>p<\/jats:italic> &lt; 0.0001), less common for stage IVB tumors, and associated with longer hospital stay (mean, 4.67 days vs 2.50 days; <jats:italic>p<\/jats:italic> &lt; 0.0001). Five\u2010year OS (5Y\u2010OS) was not significantly different between the 2 approaches (<jats:italic>p<\/jats:italic> = 0.953; open: 5Y\u2010OS, 56.5%; 95% confidence interval, 51.3% to 61.6%; endoscopic: 5Y\u2010OS, 46.0%; 95% confidence interval, 33.2% to 58.8%). In the PSM cohort of 652 patients, there was also no significant difference in OS (<jats:italic>p<\/jats:italic> = 0.850).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Endoscopic surgery is an effective alternative to open surgery, even after accounting for confounding factors that may favor its use over the open approach. It is also associated with a shorter hospital stay.<\/jats:p><\/jats:sec>","DOI":"10.1002\/alr.22040","type":"journal-article","created":{"date-parts":[[2017,12,6]],"date-time":"2017-12-06T11:43:01Z","timestamp":1512560581000},"page":"421-434","source":"Crossref","is-referenced-by-count":73,"title":["Comparison of endoscopic and open resection of sinonasal squamous cell carcinoma: a propensity score\u2013matched analysis of 652 patients"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7903-2299","authenticated-orcid":false,"given":"Suat","family":"K\u0131l\u0131\u00e7","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Rutgers New Jersey Medical School  Newark NJ"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah S.","family":"K\u0131l\u0131\u00e7","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Rutgers New Jersey Medical School  Newark NJ"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soly","family":"Baredes","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Rutgers New Jersey Medical School  Newark NJ"},{"name":"Center for Skull Base and Pituitary Surgery, Neurological Institute of New Jersey Rutgers New Jersey Medical School  Newark NJ"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Chan Woo Park","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Rutgers New Jersey Medical School  Newark NJ"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omar","family":"Mahmoud","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Rutgers New Jersey Medical School  Newark NJ"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey D.","family":"Suh","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery University of California at Los Angeles David Geffen School of Medicine  Los Angeles CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stacey T.","family":"Gray","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Harvard Medical School  Boston MA"},{"name":"Department of Otolaryngology Massachusetts Eye and Ear  Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2893-7818","authenticated-orcid":false,"given":"Jean Anderson","family":"Eloy","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Rutgers New Jersey Medical School  Newark NJ"},{"name":"Center for Skull Base and Pituitary Surgery, Neurological Institute of New Jersey Rutgers New Jersey Medical School  Newark NJ"},{"name":"Department of Neurological Surgery Rutgers New Jersey Medical School  Newark NJ"},{"name":"Department of Ophthalmology and Visual Science Rutgers New Jersey Medical School  Newark NJ"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,12,6]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(05)70311-X"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40136-016-0134-0"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2016.12.018"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.133.2.131"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.28108"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24264"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(63)90387-8"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.5152\/balkanmedj.2013.9112"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.11630"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20165"},{"key":"e_1_2_6_12_1","first-page":"110","article-title":"Delayed complications after anterior craniofacial resection of malignant skull base tumors","volume":"75","author":"Gray ST","year":"2014","journal-title":"J Neurol Surg B Skull Base"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(66)90327-8"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2017.01.001"},{"key":"e_1_2_6_15_1","first-page":"364","article-title":"An algorithm for surgical approach to the anterior skull base","volume":"77","author":"Naunheim MR","year":"2016","journal-title":"J Neurol"},{"key":"e_1_2_6_16_1","doi-asserted-by":"crossref","unstructured":"WoodJW EloyJA ViveroRJ et\u00a0al.Efficacy of transnasal endoscopic resection for malignant anterior skull\u2010base tumors. 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