{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T22:26:59Z","timestamp":1784068019348,"version":"3.55.0"},"reference-count":19,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2018,3,23]],"date-time":"2018-03-23T00:00:00Z","timestamp":1521763200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000098","name":"NIH Clinical Center","doi-asserted-by":"publisher","award":["3R01 DC005805"],"award-info":[{"award-number":["3R01 DC005805"]}],"id":[{"id":"10.13039\/100000098","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000055","name":"National Institute on Deafness and Other Communication Disorders","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000055","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Forum Allergy Rhinol"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Though many patients with chronic rhinosinusitis (CRS) describe disturbances in smell and taste, there have been no studies specifically assessing taste impairment in CRS. This study sought to objectively assess taste dysfunction in CRS patients and determine whether taste impairment correlates with olfactory dysfunction. Additionally, this investigation sought to determine the impact of taste dysfunction on quality of life (QOL) in CRS and identify the clinical factors that influence taste.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Sixty\u2010eight CRS patients were prospectively enrolled and completed several QOL surveys in relation to taste, smell, overall sinus\u2010specific QOL, and depression. Validated taste strips were used to determine gustatory dysfunction pertaining to sweet, sour, salty, and bitter. Olfactory testing was assessed using the Sniffin\u2019 Sticks Test while both Lund\u2010Kennedy and Olfactory Cleft Endoscopy Scoring (OCES) systems were used for endoscopic evaluation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The overall prevalence of dysgeusia was 28%, with scores significantly lower for sour compared to other subgroups. No correlation was observed between taste scores and objective olfactory metrics including olfaction tests and OCES. Taste scores were better in younger patients (<jats:italic>r<\/jats:italic> = 0.28, <jats:italic>p<\/jats:italic> = 0.02), female patients (<jats:italic>p<\/jats:italic> = 0.004), and never smokers compared to former smokers (<jats:italic>p<\/jats:italic> = 0.01). Taste scores did not correlate with patient\u2010reported outcome measures or CRS disease severity metrics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Taste dysfunction is a common complaint in CRS. This cohort shows prevalence of gustatory loss to be about 28% using ideal normative values. This dysfunction correlated with male gender, smoking history, and older age. Taste dysfunction did not correlate with measured olfactory outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1002\/alr.22113","type":"journal-article","created":{"date-parts":[[2018,3,23]],"date-time":"2018-03-23T08:12:22Z","timestamp":1521792742000},"page":"783-789","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Taste impairment in chronic rhinosinusitis"],"prefix":"10.1002","volume":"8","author":[{"given":"Florence","family":"Othieno","sequence":"first","affiliation":[{"name":"Division of Rhinology and Sinus Surgery Department of Otolaryngology\u2013Head and Neck Surgery, Medical University of South Carolina  Charleston SC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodney J.","family":"Schlosser","sequence":"additional","affiliation":[{"name":"Division of Rhinology and Sinus Surgery Department of Otolaryngology\u2013Head and Neck Surgery, Medical University of South Carolina  Charleston SC"},{"name":"Department of Surgery Ralph H. Johnson VA Medical Center  Charleston SC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1296-2648","authenticated-orcid":false,"given":"Nicholas R.","family":"Rowan","sequence":"additional","affiliation":[{"name":"Division of Rhinology and Sinus Surgery Department of Otolaryngology\u2013Head and Neck Surgery, Medical University of South Carolina  Charleston SC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristina A.","family":"Storck","sequence":"additional","affiliation":[{"name":"Division of Rhinology and Sinus Surgery Department of Otolaryngology\u2013Head and Neck Surgery, Medical University of South Carolina  Charleston SC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8766-1626","authenticated-orcid":false,"given":"Jose L.","family":"Mattos","sequence":"additional","affiliation":[{"name":"Division of Rhinology and Endoscopic Sinus Surgery Department of Otolaryngology\u2013Head and Neck Surgery  Charlottesville VA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6424-7083","authenticated-orcid":false,"given":"Timothy L.","family":"Smith","sequence":"additional","affiliation":[{"name":"Oregon Health &amp; Science University Department of Otolaryngology\u2013Head and Neck Surgery, Division of Rhinology and Sinus\/Skull Base Surgery  Portland OR"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zachary M.","family":"Soler","sequence":"additional","affiliation":[{"name":"Division of Rhinology and Sinus Surgery Department of Otolaryngology\u2013Head and Neck Surgery, Medical University of South Carolina  Charleston SC"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,3,23]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2009.23.3286"},{"key":"e_1_2_6_3_1","unstructured":"MattosJL SchlosserRJ DeCondeAS.Factor analysis of the questionnaire of olfactory disorders in patients with chronic rhinosinusitis. 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