{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T21:01:17Z","timestamp":1762376477922},"reference-count":28,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2018,12,21]],"date-time":"2018-12-21T00:00:00Z","timestamp":1545350400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Forum Allergy Rhinol"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The association between chronic rhinosinusitis (CRS) and chronic rhinitis remains unclear. The aim of this study was to estimate the predictive factors for sinus opacification in chronic rhinitis patients without obvious CRS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively studied a total of 332 adult patients with chronic rhinitis who visited our clinic from January 2015 to December 2017. All of the patients underwent endoscopic examination, allergy test, and osteomeatal\u2010unit computed tomography. The subjects were assigned to the normal sinus (NS) group (Lund\u2010Mackay score [LMS] &lt;5) and sinus opacification (SO) group (LMS \u22655).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 288 patients were eligible for this study. Of them, 183 (63.5%) were classified in the NS group and 105 (36.5%) in the SO group. Total immunoglobulin E (IgE) level and peripheral blood eosinophil count were significantly higher in the SO than NS group (<jats:italic>p<\/jats:italic> = 0.031 and <jats:italic>p<\/jats:italic> &lt; 0.0001, respectively). Using Pearson correlation coefficients, we determined that eosinophil count had a positive correlation with the LMS (<jats:italic>r<\/jats:italic> = 0.282). In logistic analysis, the interquartile range increase (0.19 \u00d7 10<jats:sup>9<\/jats:sup>\/L) of the eosinophil count was significantly associated with SO (odds ratio [OR] 1.76; 95% confidence interval [CI], 1.30 to 2.39). After adjusting for age, gender, smoking, drinking, and underlying disease, the interquartile range increase of the eosinophil count increased the odds of SO to 1.69\u2010fold; this increase was statistically significant (<jats:italic>p<\/jats:italic> = 0.007; 95% CI, 1.17 to 2.43).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Peripheral blood eosinophil count is an independent predictor of CRS in patients with chronic rhinitis.<\/jats:p><\/jats:sec>","DOI":"10.1002\/alr.22270","type":"journal-article","created":{"date-parts":[[2018,12,21]],"date-time":"2018-12-21T21:45:11Z","timestamp":1545428711000},"page":"522-527","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Blood eosinophils may predict radiographic sinus opacification in patients with chronic rhinitis"],"prefix":"10.1002","volume":"9","author":[{"given":"Seung Yong","family":"Oh","sequence":"first","affiliation":[{"name":"Department of Otolaryngology National Police Hospital  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junho","family":"Hwang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology National Police Hospital  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoon\u2010Jong","family":"Ryu","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Kangwon National University Hospital  Chuncheon Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun Yeon","family":"Won","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Kangwon National University Hospital  Chuncheon Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung Ok","family":"Kwon","sequence":"additional","affiliation":[{"name":"Biomedical Research Institute Kangwon National University Hospital  Chuncheon Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Woo Hyun","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Kangwon National University Hospital  Chuncheon Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,12,21]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11882-014-0439-3"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2004.09.029"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.4193\/Rhino12.000"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.21553"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2011.02646.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11882-012-0242-y"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1081-1206(10)60829-0"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.1996.tb01009.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2007.02.004"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.21394"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2001.119324"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(88)90944-X"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1053\/ajot.2001.22570"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.3390\/medicina44040033"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2014.28.4024"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215116009324"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2017.31.4405"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/MLG.0b013e31817d01b8"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2249.2004.02530.x"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2008.02.010"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1398-9995.1999.00813.x"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.20025"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016489409124320"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016489409124319"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.2500\/ajr.2006.20.2907"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1017\/S002221511700192X"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200307000-00016"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.126.8.940"}],"container-title":["International Forum of Allergy &amp; 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