{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T19:39:30Z","timestamp":1787859570132,"version":"build-2784847793"},"reference-count":1421,"publisher":"Wiley","issue":"S3","license":[{"start":{"date-parts":[[2019,7,22]],"date-time":"2019-07-22T00:00:00Z","timestamp":1563753600000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Forum Allergy Rhinol"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Endoscopic skull\u2010base surgery (ESBS) is employed in the management of diverse skull\u2010base pathologies. Paralleling the increased utilization of ESBS, the literature in this field has expanded rapidly. However, the rarity of these diseases, the inherent challenges of surgical studies, and the continued learning curve in ESBS have resulted in significant variability in the quality of the literature. To consolidate and critically appraise the available literature, experts in skull\u2010base surgery have produced the International Consensus Statement on Endoscopic Skull\u2010Base Surgery (ICAR:ESBS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Using previously described methodology, topics spanning the breadth of ESBS were identified and assigned a literature review, evidence\u2010based review or evidence\u2010based review with recommendations format. Subsequently, each topic was written and then reviewed by skull\u2010base surgeons in both neurosurgery and otolaryngology. Following this iterative review process, the ICAR:ESBS document was synthesized and reviewed by all authors for consensus.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The ICAR:ESBS document addresses the role of ESBS in primary cerebrospinal fluid (CSF) rhinorrhea, intradural tumors, benign skull\u2010base and orbital pathology, sinonasal malignancies, and clival lesions. Additionally, specific challenges in ESBS including endoscopic reconstruction and complication management were evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>A critical review of the literature in ESBS demonstrates at least the equivalency of ESBS with alternative approaches in pathologies such as CSF rhinorrhea and pituitary adenoma as well as improved reconstructive techniques in reducing CSF leaks. Evidence\u2010based recommendations are limited in other pathologies and these significant knowledge gaps call upon the skull\u2010base community to embrace these opportunities and collaboratively address these shortcomings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/alr.22326","type":"journal-article","created":{"date-parts":[[2019,7,22]],"date-time":"2019-07-22T10:45:01Z","timestamp":1563792301000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":118,"title":["ICAR: endoscopic skull\u2010base surgery"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1180-5854","authenticated-orcid":false,"given":"Eric W.","family":"Wang","sequence":"first","affiliation":[{"name":"University of Pittsburgh Pittsburgh PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam M.","family":"Zanation","sequence":"additional","affiliation":[{"name":"University of North Carolina Chapel 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