{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T05:13:12Z","timestamp":1785301992366,"version":"3.55.0"},"reference-count":23,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2019,9,12]],"date-time":"2019-09-12T00:00:00Z","timestamp":1568246400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81371104"],"award-info":[{"award-number":["81371104"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Forum Allergy Rhinol"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Grass pollen is the most prevalent sensitizing aeroallergen to cause respiratory allergies in northern China. Air pollutants have a substantial effect on respiratory health and some pollens. This study aimed to investigate relationships among airborne grass pollen, air pollutants and allergic diseases, in order to determine their effects on patients with grass pollen allergies in Beijing, China, during the period from 2013 to 2016.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data regarding autumnal grass pollens and air pollutants measured in Beijing from 2012 to 2016 were obtained from local governmental agencies. Patient data regarding specific immunoglobulin E (IgE) analyses from 2013 to 2016 were obtained from the Department of Allergy in Beijing Tongren Hospital. Spearman's rank correlation analysis was used to assess associations between the daily number of grass pollen allergen\u2013positive patients and the following parameters: 3 clinically\u2010relevant grass pollen genera (<jats:italic>Artemisia<\/jats:italic>, <jats:italic>Humulus<\/jats:italic>, and <jats:italic>Chenopodium<\/jats:italic>) and inhalable pollutants.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Correlation analysis indicated that the daily number of grass pollen\u2010positive patients was significantly associated with the peak period of grass pollens, as well as pollutants SO<jats:sub>2<\/jats:sub> and NOx. Moreover, concentrations of air pollutants (eg, ozone, oxides of nitrogen [NO<jats:sub>x<\/jats:sub>], and SO<jats:sub>2<\/jats:sub>) were consistently and significantly associated with concentrations of grass pollens; particulate matter 2.5 \u00b5m in diameter was negatively associated with <jats:italic>Artemisia<\/jats:italic> and <jats:italic>Chenopodium<\/jats:italic> pollens.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Grass pollens exhibited substantial impact on allergic disease morbidity. Air pollutants impacted allergic disease and grass pollen. Thus, public health and clinical approaches to anticipate and reduce allergic disease morbidity from pollen and pollutants are needed.<\/jats:p><\/jats:sec>","DOI":"10.1002\/alr.22389","type":"journal-article","created":{"date-parts":[[2019,9,12]],"date-time":"2019-09-12T18:09:17Z","timestamp":1568311757000},"page":"1297-1303","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Associations among air pollutants, grass pollens, and daily number of grass pollen allergen\u2010positive patients: a longitudinal study from 2012 to 2016"],"prefix":"10.1002","volume":"9","author":[{"given":"Yuhui","family":"Ouyang","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery and Department of Allergy Beijing Tongren Hospital, Affiliated to the Capital University of Medical Science  Beijing China"},{"name":"Beijing Key Laboratory of Nasal Diseases Beijing Institute of Otolaryngology  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaoyin","family":"Yin","sequence":"additional","affiliation":[{"name":"Beijing Weather Information Service  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Li","sequence":"additional","affiliation":[{"name":"Beijing Key Laboratory of Nasal Diseases Beijing Institute of Otolaryngology  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erzhong","family":"Fan","sequence":"additional","affiliation":[{"name":"Beijing Key Laboratory of Nasal Diseases Beijing Institute of Otolaryngology  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0910-9884","authenticated-orcid":false,"given":"Luo","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery and Department of Allergy Beijing Tongren Hospital, Affiliated to the Capital University of Medical Science  Beijing China"},{"name":"Beijing Key Laboratory of Nasal Diseases Beijing Institute of Otolaryngology  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,9,12]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2013.10.035"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.4168\/aair.2014.6.2.105"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-10111-9"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.13388"},{"key":"e_1_2_6_6_1","first-page":"272","article-title":"Onset feature and efficacy of early interventional treatment of Artemisia pollinosis","volume":"49","author":"Ouyang Y","year":"2014","journal-title":"Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2008.12.003"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13280-012-0288-z"},{"key":"e_1_2_6_9_1","first-page":"205","article-title":"Role of air pollution on pathogenesis of asthma and allergic diseases","volume":"2","author":"Hashemi A","year":"2018","journal-title":"J Air Pollut Health"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.21632"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2017.04.206"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10453-017-9478-2"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2017.02.032"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12940-015-0057-0"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph14030226"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1159\/000332964"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2016.10.016"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12011-011-9290-8"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11356-016-7554-8"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2016.04.076"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1159\/000091600"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-10721-3"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40629-014-0003-7"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.3390\/atmos8020022"}],"container-title":["International Forum of Allergy &amp; 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