{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T18:42:57Z","timestamp":1787856177447,"version":"build-2784847793"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,1,14]],"date-time":"2020-01-14T00:00:00Z","timestamp":1578960000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Forum Allergy Rhinol"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Surgical treatment of chronic rhinosinusitis with nasal polyposis (CRSwNP) has evolved over the last decade as rhinologists have increasingly used topical steroid therapies and altered surgical techniques. It is important to understand the changes in success rates of surgery and frequency of revision endoscopic sinus surgery (ESS) in CRSwNP. The aim of this study was to retrospectively review the revision surgical rate of CRSwNP patients by evaluating outcomes in a cohort from the Medical University of South Carolina (MUSC).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective review of CRSwNP patients operated upon at the MUSC between 2002 and 2019 by a single surgeon was performed. Assessed factors included demographics, comorbidities, CRSwNP subtype, extent of surgery, and steroid rinse compliance. Logistic regression was performed to identify factors associated with revision surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 338 patients with at least 6 months of follow\u2010up, 24.9% had revision surgery, with a mean follow\u2010up of 52.6 months. In patients with any person\u2010time measure, the revision rate was 5.58 per 100 person\u2010years. Independent risk factors associated with increased odds ratio (OR) for revision surgery were: younger age (OR, 1.1); prior surgery (OR, 3.3); longer follow\u2010up (OR, 1.1); and surgery before 2009 (OR, 2.4) (<jats:italic>p<\/jats:italic> &lt; 0.05 for all).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The revision surgery rate for CRSwNP was 24.9% among those with at least 6 months of follow\u2010up. Risk factors for higher revision rates included younger age, previous surgery, longer follow\u2010up, and surgery at the MUSC prior to 2009. As we enter an era of personalized medicine, it is important to consider patient\u2010 and surgeon\u2010specific factors, which impact revision surgery rates.<\/jats:p><\/jats:sec>","DOI":"10.1002\/alr.22505","type":"journal-article","created":{"date-parts":[[2020,1,14]],"date-time":"2020-01-14T09:40:16Z","timestamp":1578994816000},"page":"289-302","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":48,"title":["Factors impacting revision surgery in patients with chronic rhinosinusitis with nasal polyposis"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2372-3431","authenticated-orcid":false,"given":"Catherine A.","family":"Loftus","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Medical University of South Carolina  Charleston SC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zachary 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