{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T23:47:17Z","timestamp":1780098437879,"version":"3.54.0"},"reference-count":147,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2020,12,4]],"date-time":"2020-12-04T00:00:00Z","timestamp":1607040000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Forum Allergy Rhinol"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Rhinologic disease can be responsible for systemic symptoms affecting mood, cognition, and sleep. It is unclear whether sleep disturbance in specific rhinologic disorders (chronic rhinosinusitis [CRS], rhinitis, and nasal septal deviation [NSD]) is an obstructive phenomenon or due to other mechanisms. In this review we examine the impact of CRS, rhinitis, and NSD on objective and subjective sleep outcome metrics and draw comparisons to normal controls and patients with known obstructive sleep apnea (OSA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A systematic review of 4 databases (PubMed, Scopus, Cochrane Library, and Web of Science) was performed. Studies reporting on objective (apnea\u2010hypopnea index [AHI], respiratory disturbance index [RDI], oxygen nadir) and subjective (Epworth Sleepiness Scale [EpSS], Pittsburgh Sleep Quality Index [PSQI], Fatigue Severity Scale [FSS]) sleep parameters and disease\u2010specific patient\u2010reported outcome measures (PROMs; 22\u2010item Sino\u2010Nasal Outcome Test [SNOT\u201022], Rhinoconjunctivitis Quality of Life Questionnaire [RQLQ], Nasal Obstruction Symptom Evaluation [NOSE]) were included.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The database search yielded 1414 unique articles, of which 103 were included for analysis. Baseline PROMs were at the high end of normal to abnormal for all 3 conditions: EpSS: CRS (9.8 \u00b1 4.0), rhinitis (9.7 \u00b1 4.3), and NSD (8.9 \u00b1 4.6); and PSQI: CRS (11.0 \u00b1 4.5), rhinitis (6.1 \u00b1 3.7), and NSD (8.6 \u00b1 3.5). Objective measures demonstrated a mild to moderate OSA in the studied diseases: AHI: CRS (10.4 \u00b1 11.5), rhinitis (8.6 \u00b1 8.8), and NSD (13.0 \u00b1 6.9). There were significant differences when compared with reported norms in all measured outcomes (<jats:italic>p<\/jats:italic>&lt; 0.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Sleep quality is impacted by rhinologic (CRS, rhinitis, NSD) disease. There is likely a mild obstructive component contributing to poor sleep, but other contributing factors may be involved.<\/jats:p><\/jats:sec>","DOI":"10.1002\/alr.22740","type":"journal-article","created":{"date-parts":[[2020,12,4]],"date-time":"2020-12-04T17:37:35Z","timestamp":1607103455000},"page":"1074-1086","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Rhinologic disease and its impact on sleep: a systematic review"],"prefix":"10.1002","volume":"11","author":[{"given":"Jacob","family":"Fried","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2012Head and Neck Surgery Medical University of South Carolina Charleston SC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2704-1086","authenticated-orcid":false,"given":"Erick","family":"Yuen","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2012Head and Neck Surgery Medical University of South Carolina Charleston SC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andraia","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2012Head and Neck Surgery Medical University of South Carolina Charleston SC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathy","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2012Head and Neck Surgery Medical University of South Carolina Charleston SC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaun A.","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2012Head and Neck Surgery Medical University of South Carolina Charleston SC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Gudis","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2012Head and Neck Surgery Columbia University Irving Medical Center New York NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1296-2648","authenticated-orcid":false,"given":"Nicholas R.","family":"Rowan","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2012Head and Neck Surgery The Johns Hopkins University School of Medicine Baltimore MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodney J.","family":"Schlosser","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2012Head and Neck Surgery Medical University of South Carolina Charleston SC"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,12,4]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.21843"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.22406"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.5606\/kbbihtisas.2011.048"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-014-3067-6"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.2011.03935.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2004.08.044"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.22212"},{"issue":"1","key":"e_1_2_6_9_1","article-title":"Chronic rhinosinusitis impairs sleep quality: results of the GA2LEN Study","volume":"40","author":"Bengtsson C","year":"2017","journal-title":"Sleep"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.21860"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.21682"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/sbr.12026"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/7951045"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-018-5229-4"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599817737977"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/0003489419851527"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/EDE.0b013e3181fe7825"},{"key":"e_1_2_6_18_1","unstructured":"Oxford Centre for Evidence\u2010Based Medicine.2016.https:\/\/www.cebm.net\/2016\/05\/ocebm-levels-of-evidence. 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