{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T09:00:41Z","timestamp":1789981241732,"version":"4.0.1"},"reference-count":38,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,5,9]],"date-time":"2023-05-09T00:00:00Z","timestamp":1683590400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Forum Allergy Rhinol"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:label\/><jats:p>A patient\u2010reported history of penicillin allergy is a common label with a prevalence of about 10%. However, as many as 95% of patients reporting a penicillin allergy do not have a true immunoglobin\u2010E (IgE)\u2010mediated allergic reaction. Unfortunately, penicillin allergy mislabeling is problematic, leading to inappropriate antibiotic use and negative consequences, such as adverse drug events, suboptimal outcomes, and increased costs. As physicians who treat patients of all ages for common sinonasal pathology in the clinic and operating room in addition to frequently providing testing and management of allergic diseases, rhinologists are well positioned to aid in delabeling patients with inaccurate penicillin allergies. This viewpoint highlights the consequences of inaccurate penicillin allergy designation in the clinic and perioperative period and explores misconceptions regarding cross\u2010reactivity between penicillins and cephalosporins. Opportunities are explored for shared decision\u2010making with colleagues in other specialties, such as anesthesiology, and practical recommendations are provided to aid rhinologists when faced with a patient who holds a questionable history of penicillin allergy. Rhinologists can play an active role in delabeling patients with inaccurate penicillin allergies with the goal of ensuring appropriate antibiotic use for future medical encounters.<\/jats:p><\/jats:sec>","DOI":"10.1002\/alr.23173","type":"journal-article","created":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T00:54:25Z","timestamp":1682556865000},"page":"973-978","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Inaccurate penicillin allergy labels: Consequences, solutions, and opportunities for rhinologists"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9114-6571","authenticated-orcid":false,"given":"Matthew Y.","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery University of Texas Health San Antonio  San Antonio Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1812-2105","authenticated-orcid":false,"given":"Edward D.","family":"McCoul","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Ochsner Health System  New Orleans Louisiana USA"},{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery Tulane University School of Medicine  New Orleans Louisiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward G.","family":"Brooks","sequence":"additional","affiliation":[{"name":"Department of Pediatric \u2013 Immunology and Infectious Disease University of Texas Health San Antonio  San Antonio Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronica F.","family":"Lao","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology University of Texas Health San Antonio  San Antonio Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5468-3324","authenticated-orcid":false,"given":"Philip G.","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery University of Texas Health San Antonio  San Antonio Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,5,9]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2022.14153"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2022.08.028"},{"issue":"2","key":"e_1_2_8_4_1","first-page":"S1","article-title":"Clinical practice guideline (Update): adult sinusitis","volume":"152","author":"Rosenfeld RM","year":"2015","journal-title":"Otolaryngol Head Neck Surg"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.22741"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.22085"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2018.19283"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.13848"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.6510"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1159\/000526424"},{"issue":"1","key":"e_1_2_8_11_1","first-page":"1","article-title":"Antimicrobial treatment guidelines for acute bacterial rhinosinusitis","volume":"130","author":"Anon JB","year":"2004","journal-title":"Otolaryngol Head Neck Surg"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.4151"},{"issue":"9","key":"e_1_2_8_13_1","first-page":"651","article-title":"Update on the adverse effects of antimicrobial therapies in community practice","volume":"66","author":"Mohsen S","year":"2020","journal-title":"Can Fam Physician"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199512143332404"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anai.2020.08.003"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2017.12.033"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.waojou.2021.100549"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-020-01269-2"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cix794"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.3928\/01477447-20190604-03"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2017.0904"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.25856"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000003419"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2017.07.033"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0000000000002252"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2021.03.022"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2021.08.147"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.5435\/JAAOS-D-18-00709"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.22756"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02176-12"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2020.04.058"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciaa194"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.30329"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13223-020-00494-2"},{"key":"e_1_2_8_35_1","unstructured":"CPT codes and expected reimbursement for drug allergy testing and oral challenge.American College of Allergy Asthma & Immunology.2015. Accessed March 24 2023.https:\/\/college.acaai.org\/sites\/default\/files\/CPT%20codes%20and%20expected%20reimbursement%20for%20drug%20allergy%20testing%20and%20oral%20challenge.pdf"},{"key":"e_1_2_8_36_1","volume-title":"LiverTox: Clinical and Research Information on Drug\u2010Induced Liver Injury","year":"2012"},{"key":"e_1_2_8_37_1","volume-title":"LiverTox: Clinical and Research Information on Drug\u2010Induced Liver Injury","year":"2012"},{"key":"e_1_2_8_38_1","volume-title":"LiverTox: Clinical and Research Information on Drug\u2010Induced Liver Injury","year":"2012"},{"key":"e_1_2_8_39_1","volume-title":"LiverTox: Clinical and Research Information on Drug\u2010Induced Liver Injury","year":"2012"}],"container-title":["International Forum of Allergy &amp; Rhinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/alr.23173","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,20]],"date-time":"2023-08-20T00:02:28Z","timestamp":1692489748000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/alr.23173"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,9]]},"references-count":38,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["10.1002\/alr.23173"],"URL":"https:\/\/doi.org\/10.1002\/alr.23173","archive":["Portico"],"relation":{},"ISSN":["2042-6976","2042-6984"],"issn-type":[{"value":"2042-6976","type":"print"},{"value":"2042-6984","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,9]]},"assertion":[{"value":"2023-02-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-23","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-09","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}