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This study aimed to translate the CRS\u2010PRO questionnaire into Chinese and assess its reliability, validity, and responsiveness to provide Chinese patients with a more concise and efficient subjective assessment instrument.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The Chinese version of the CRS\u2010PRO was created through forward\u2010backward translations and cultural adaptation. Here, 168 CRS patients (118 patients CRS with nasal polyps [CRSwNP] and 50 patients with CRS without nasal polyps [CRSsNP]) and 43 healthy individuals were enrolled. All participants completed the CRS\u2010PRO, 22\u2010item Sinonasal Outcome Test (SNOT\u201022), and EuroQol five dimensions questionnaire (EQ\u20105D) questionnaires preoperatively as well as 3 and 6 months after surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The Chinese version of the CRS\u2010PRO demonstrated good internal consistency, with a Cronbach's <jats:italic>\u03b1<\/jats:italic> of 0.813. It also exhibited a higher criterion validity (<jats:italic>r<\/jats:italic>\u00a0=\u00a00.65, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.05) than the SNOT\u201022. A moderate association was found between the CRS\u2010PRO and objective indicators such as the Lund\u2013Mackay and endoscopic scores. Furthermore, the CRS\u2010PRO, like the SNOT\u201022, could clearly distinguish CRS patients from healthy subjects (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.01), as well as between the CRSwNP and CRSsNP subtypes (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.01). Additionally, changes in the CRS\u2010PRO exhibited a larger effect size compared to changes in the SNOT\u201022 (Cohen's <jats:italic>d<\/jats:italic>\u00a0=\u00a01.05 and 0.93 vs. 0.71 and 0.90 for 3 and 6 months, respectively, all <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The Chinese version of the CRS\u2010PRO is a concise, reliable, and responsive instrument that can be utilized as a novel subjective evaluation tool for future clinical practice.<\/jats:p><\/jats:sec>","DOI":"10.1002\/alr.23285","type":"journal-article","created":{"date-parts":[[2023,10,12]],"date-time":"2023-10-12T08:14:13Z","timestamp":1697098453000},"page":"950-960","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Chinese adaptation and validation of the chronic rhinosinusitis\u2010patient\u2010reported outcome: Assessment of health\u2010related quality\u2010of\u2010life"],"prefix":"10.1002","volume":"14","author":[{"given":"Jiani","family":"Chen","sequence":"first","affiliation":[{"name":"ENT Institute and Department of Otorhinolaryngology Eye &amp; ENT Hospital Fudan University  Shanghai P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Hu","sequence":"additional","affiliation":[{"name":"ENT Institute and Department of Otorhinolaryngology Eye &amp; ENT Hospital Fudan University  Shanghai P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Zhang","sequence":"additional","affiliation":[{"name":"ENT Institute and Department of Otorhinolaryngology Eye &amp; ENT Hospital Fudan University  Shanghai P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Le","family":"Shi","sequence":"additional","affiliation":[{"name":"ENT Institute and Department of Otorhinolaryngology Eye &amp; ENT Hospital Fudan University  Shanghai P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qianqian","family":"Zhang","sequence":"additional","affiliation":[{"name":"ENT Institute and Department of Otorhinolaryngology Eye &amp; ENT Hospital Fudan University  Shanghai P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yumin","family":"Zhou","sequence":"additional","affiliation":[{"name":"ENT Institute and Department of Otorhinolaryngology Eye &amp; ENT Hospital Fudan University  Shanghai P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fuying","family":"Cheng","sequence":"additional","affiliation":[{"name":"ENT Institute and Department of Otorhinolaryngology Eye &amp; ENT Hospital Fudan University  Shanghai P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingqi","family":"Gao","sequence":"additional","affiliation":[{"name":"ENT Institute and Department of Otorhinolaryngology Eye &amp; ENT Hospital Fudan University  Shanghai P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Houyong","family":"Li","sequence":"additional","affiliation":[{"name":"ENT Institute and Department of Otorhinolaryngology Eye &amp; ENT Hospital Fudan University  Shanghai P. R. China"},{"name":"Refractory Chronic Sinusitis Clinical Center of Eye &amp; ENT Hospital of Fudan University  Shanghai P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0346-3193","authenticated-orcid":false,"given":"Dehui","family":"Wang","sequence":"additional","affiliation":[{"name":"ENT Institute and Department of Otorhinolaryngology Eye &amp; ENT Hospital Fudan University  Shanghai P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huan","family":"Wang","sequence":"additional","affiliation":[{"name":"ENT Institute and Department of Otorhinolaryngology Eye &amp; ENT Hospital Fudan University  Shanghai P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xicai","family":"Sun","sequence":"additional","affiliation":[{"name":"ENT Institute and Department of Otorhinolaryngology Eye &amp; ENT Hospital Fudan University  Shanghai P. R. 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