{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T04:42:02Z","timestamp":1754109722993,"version":"3.40.5"},"reference-count":23,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2024,6,6]],"date-time":"2024-06-06T00:00:00Z","timestamp":1717632000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Forum Allergy Rhinol"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Improved nasal airway obstruction (NAO) symptoms were reported at 3 months following temperature\u2010controlled radiofrequency (TCRF) treatment of the septal swell body (SSB). This report provides results from assessments of the long\u2010term safety and efficacy of TCRF treatment of SSB hypertrophy to treat NAO through 12 months posttreatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This prospective, multicenter, long\u2010term, open\u2010label study was conducted in nine centers within the United States and included patients with severe\/extreme NAO attributed to SSB hypertrophy. Outcome measures included assessments of Nasal Obstruction Symptom Evaluation Score (NOSE), Numeric Rating Scale (NRS) ease\u2010of\u2010breathing, patient satisfaction, and adverse events at 6 and 12 months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 70 patients treated, 65 and 62 patients completed the 6\u2010 and 12\u2010month follow\u2010up assessments. Compared to baseline, there was a 67.5% decrease in adjusted mean NOSE scores at 6 months (mean change \u221249.6, 95% confidence interval [CI] \u221254.8 to \u221244.4; <jats:italic>p\u00a0<\/jats:italic>&lt;\u00a00.001) and a 65.4% decrease at 12 months (mean change \u221248.1, 95% CI \u221253.7 to \u221242.5); <jats:italic>p\u00a0<\/jats:italic>&lt;\u00a00.001), which is consistent with previously published 3\u2010month results. A 62.0% and 62.5% improvement compared to baseline was observed in the NRS ease\u2010of\u2010breathing score at 6 and 12 months, respectively (<jats:italic>p\u00a0<\/jats:italic>&lt;\u00a00.001). No serious adverse were reported overall and no new device\u2010 or procedure\u2010related adverse events were reported in the interval between 3 and 12 months posttreatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>TCRF treatment of SSB hypertrophy has a significant and durable effect on improving the symptoms of NAO and health\u2010related quality of life in patients with symptoms of nasal obstruction and congestion through 12 months postprocedure.<\/jats:p><\/jats:sec>","DOI":"10.1002\/alr.23383","type":"journal-article","created":{"date-parts":[[2024,6,6]],"date-time":"2024-06-06T12:34:32Z","timestamp":1717677272000},"page":"1549-1557","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Twelve\u2010month outcomes following temperature\u2010controlled radiofrequency treatment of the septal swell body for nasal airway obstruction"],"prefix":"10.1002","volume":"14","author":[{"given":"Jordan","family":"Pritikin","sequence":"first","affiliation":[{"name":"Chicago Nasal &amp; Sinus Center  Chicago Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stacey","family":"Silvers","sequence":"additional","affiliation":[{"name":"Madison ENT &amp; Facial Plastic Surgery  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey","family":"Rosenbloom","sequence":"additional","affiliation":[{"name":"Alamo ENT Associates  San Antonio Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bryan","family":"Davis","sequence":"additional","affiliation":[{"name":"Colorado ENT &amp; Allergy  Colorado Springs Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony Del","family":"Signore","sequence":"additional","affiliation":[{"name":"Mount Sinai Hospital  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6331-2325","authenticated-orcid":false,"given":"Ahmad R.","family":"Sedaghat","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery University of Cincinnati College of Medicine  Cincinnati Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bobby A.","family":"Tajudeen","sequence":"additional","affiliation":[{"name":"Rush University Medical Center  Chicago Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isaac","family":"Schmale","sequence":"additional","affiliation":[{"name":"University of Rochester Medical Center  Rochester New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rakesh","family":"Chandra","sequence":"additional","affiliation":[{"name":"Vanderbilt University Medical Center  Nashville Tennessee USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,6,6]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12901\u2010016\u20130031\u20137"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.25144"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archoto.2010.201"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.2478\/rjr\u20102020\u20100004"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2005.10.058"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2019.03.003"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.28621"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.22861"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/lio2.1089"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.23156"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405\u2010018\u201005270\u2010y"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otot.2019.10.001"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2003.09.016"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamafacial.2013.344"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599817701719"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/lio2.759"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2003.12.004"},{"issue":"11","key":"e_1_2_8_19_1","first-page":"1016","article-title":"Radiofrequency ablation of septal swell body","volume":"2","author":"Catalano PJ","year":"2015","journal-title":"Ann Otolaryngol Rhinol"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1017\/s0022215120000675"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.25154"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2019.03.003"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2021.103165"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/scs.0000000000006107"}],"container-title":["International Forum of Allergy &amp; 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