{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T15:51:36Z","timestamp":1778773896008,"version":"3.51.4"},"reference-count":21,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2024,9,2]],"date-time":"2024-09-02T00:00:00Z","timestamp":1725235200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Forum Allergy Rhinol"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Accurate conflict of interest (COI) information is essential for promoting transparency and trust in research. We aim to assess COI disclosure patterns in monoclonal antibodies (MABs) research for chronic rhinosinusitis with nasal polyposis (CRSwNP) using the Open Payments Database (OPD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Studies on FDA\u2010approved MABs for CRSwNP (dupilumab, omalizumab, mepolizumab) published between 2019 and 2021 with at least one US author were identified through PubMed. Industry\u2010reported payments from the manufacturers (Sanofi, Regeneron, Genentech, Novartis, and GlaxoSmithKline) between 2018 and 2021 in OPD's General Payments category were collected. Authors were cross\u2010checked against OPD metadata using a previously published ChatGPT\u2010based algorithm. Additionally, this novel algorithm analyzed COI statements for relevant author\u2012company specific disclosures, identifying disclosed and undisclosed payments made 3\u201215 months prior to publication.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 214 unique authors from 76 studies were included. Of 30 articles that received at least one relevant payment, 21 (70%) were found to have an undisclosed COI, with a mean total undisclosed payment of $4890 and a median of $10,331. Fifty\u2010six authors had relevant OPD payments and 40 (71.4%) authors did not declare a potential COI. Interestingly, 158 authors had no relevant payments and 62 (39.2%) declared a potential COI. Author order was not significantly associated with potential under\u2010 or over\u2010disclosure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study characterizes COI disclosure patterns in rhinosinusitis\u2010relevant MABs research using a novel automated approach. Given the discrepancy between disclosures and industry\u2010reported payments, our findings suggest a need for improved disclosure education and practices.<\/jats:p><\/jats:sec>","DOI":"10.1002\/alr.23447","type":"journal-article","created":{"date-parts":[[2024,9,2]],"date-time":"2024-09-02T15:09:46Z","timestamp":1725289786000},"page":"1904-1913","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Assessment of conflicts of interest in literature on monoclonal antibodies for chronic rhinosinusitis with nasal polyposis using the Open Payments Database"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9380-1007","authenticated-orcid":false,"given":"Christina","family":"Liu","sequence":"first","affiliation":[{"name":"Division of Otolaryngology Department of Surgery Yale School of Medicine  New Haven Connecticut USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Conrad W.","family":"Safranek","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology Department of Surgery Yale School of Medicine  New Haven Connecticut USA"},{"name":"Section for Biomedical Informatics and Data Science Yale University School of Medicine  New Haven Connecticut USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rhys","family":"Richmond","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology Department of Surgery Yale School of Medicine  New Haven Connecticut USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Trinithas","family":"Boyi","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology Department of Surgery Yale School of Medicine  New Haven Connecticut USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zachary","family":"Pickell","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology Department of Surgery Yale School of Medicine  New Haven Connecticut USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan","family":"Rimmer","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology Department of Surgery Yale School of Medicine  New Haven Connecticut USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. 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