{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T20:34:41Z","timestamp":1762202081194,"version":"build-2065373602"},"reference-count":31,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T00:00:00Z","timestamp":1751414400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["RS\u20102022\u2010NR074242"],"award-info":[{"award-number":["RS\u20102022\u2010NR074242"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Forum Allergy Rhinol"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate the impact of the extent of resection and adjuvant radiotherapy (RT) on treatment outcomes in patients with early\u2010stage olfactory neuroblastoma (ONB) without definite dural invasion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective review of ONB cases from two centers within a single institution between 1992 and 2023 was performed. Clinicopathologic data included tumor stage, grade, treatment modalities, margin status, follow\u2010up time, and survival. Survival outcomes, including overall survival (OS), disease\u2010free survival (DFS), and local recurrence\u2010free survival (LFS), were analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 118 ONB patients, 38 were included in the final cohort, with most (76.3%) classified as modified Kadish (mKadish) stage A or B. The 10\u2010year DFS and LFS rates were 68.5% and 89.7%, respectively. No local recurrence occurred in patients who underwent transdural resection with negative margins, regardless of adjuvant RT. Extradural resection with adjuvant RT significantly improved LFS compared to extradural resection alone (log\u2010rank\n                      <jats:italic>p<\/jats:italic>\n                      = 0.032). Pathologic dura involvement was identified in four (19.0%) of 21 patients who underwent transdural resection. No significant difference in oncologic outcomes between unilateral and bilateral resections was observed when transdural resection was performed for unilateral disease.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Transdural resection with negative surgical margins, regardless of adjuvant RT, or extradural resection with adjuvant RT, demonstrated excellent local control. Extradural resection alone was associated with a higher risk of local recurrence. Unilateral transdural resection can be feasible for unilateral disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/alr.23625","type":"journal-article","created":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T08:25:27Z","timestamp":1751444727000},"page":"1238-1244","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Extent of Resection and Role of Adjuvant Radiotherapy in Olfactory Neuroblastoma Without Definite Radiologic Evidence of Dural Invasion"],"prefix":"10.1002","volume":"15","author":[{"given":"Tae\u2010Bin","family":"Won","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery Seoul National University Hospital Seoul National University College of Medicine  Seoul South Korea"},{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery Seoul National University Bundang Hospital Seoul National University College of Medicine  Seongnam South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4612-7624","authenticated-orcid":false,"given":"Minju","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery National Medical Center  Seoul South Korea"},{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery Seoul National University College of Medicine  Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0827-4471","authenticated-orcid":false,"given":"Sung\u2010Woo","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery Seoul National University Bundang Hospital Seoul National University College of Medicine  Seongnam South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3367-1495","authenticated-orcid":false,"given":"Doo Hee","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery Seoul National University Hospital Seoul National University College of Medicine  Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyun Jik","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery Seoul National University Hospital Seoul National University College of Medicine  Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong\u2010Young","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery Seoul National University Hospital Seoul National University College of Medicine  Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chae\u2010Seo","family":"Rhee","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery Seoul National University Bundang Hospital Seoul National University College of Medicine  Seongnam South Korea"},{"name":"Sensory Organ Research Institute Seoul National University Medical Research Center  Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kihwan","family":"Hwang","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Seoul National University Bundang Hospital Seoul National University College of Medicine  Seongnam South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sun Ha","family":"Paek","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Seoul National University Hospital Seoul National University College of Medicine  Seoul South 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