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Points<\/jats:title>\n                    <jats:p>\n                      <jats:list list-type=\"bullet\">\n                        <jats:list-item>\n                          <jats:p>An untargeted transcriptomic analysis provided exploratory insight into key genes and pathways that can be used to help identify patients at risk for surgically refractory chronic rhinosinusitis with nasal polyps (CRSwNP).<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>The Charcot\u2013Leyden crystal gene, periostin and osteopontin\u2010associated pathways, eicosanoid synthesis pathway, and prostaglandin\/leukotriene metabolism pathway, among others, are associated with dupilumab prescription for surgically refractory chronic rhinosinusitis and may support early stratification of disease severity in CRSwNP patients.<\/jats:p>\n                        <\/jats:list-item>\n                      <\/jats:list>\n                 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