{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T04:51:29Z","timestamp":1789102289854,"version":"build-2803163510"},"reference-count":31,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2021,7,23]],"date-time":"2021-07-23T00:00:00Z","timestamp":1626998400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["alz-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Alzheimer's &amp;amp; Dementia"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Effective strategies to recruit older adults with mild cognitive impairment (MCI) into nonpharmacological intervention trials are lacking.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Recruitment for EXERT, a multisite randomized controlled 18\u2010month trial examining the effects of aerobic exercise on cognitive trajectory in adults with amnestic MCI, involved a diverse portfolio of strategies to enroll 296 participants.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Recruitment occurred September 2016 through March 2020 and was initially slow. After mass mailings of 490,323 age\u2010 and geo\u2010targeted infographic postcards and brochures, recruitment rates increased substantially, peaking at 16 randomizations\/month in early 2020. Mass mailings accounted for 52% of randomized participants, whereas 25% were recruited from memory clinic rosters, electronic health records, and national and local registries. Other sources included news broadcasts, public service announcements (PSA), local advertising, and community presentations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Age\u2010 and geo\u2010targeted mass mailing of infographic materials was the most effective approach in recruiting older adults with amnestic MCI into an 18\u2010month exercise trial.<\/jats:p><\/jats:sec>","DOI":"10.1002\/alz.12401","type":"journal-article","created":{"date-parts":[[2021,7,23]],"date-time":"2021-07-23T15:48:42Z","timestamp":1627055322000},"page":"1808-1817","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Recruitment of a multi\u2010site randomized controlled trial of aerobic exercise for older adults with amnestic mild cognitive impairment: The EXERT trial"],"prefix":"10.1002","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9693-0522","authenticated-orcid":false,"given":"Aladdin H.","family":"Shadyab","sequence":"first","affiliation":[{"name":"Herbert Wertheim School of Public Health and Human Longevity Science University of California, San Diego  La Jolla California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea Z.","family":"LaCroix","sequence":"additional","affiliation":[{"name":"Herbert Wertheim School of Public Health and Human Longevity Science University of California, San Diego  La Jolla California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Howard H.","family":"Feldman","sequence":"additional","affiliation":[{"name":"Department of Neurosciences Alzheimer's Disease Cooperative Study University of California, San Diego  La Jolla California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher H.","family":"van Dyck","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Yale University School of Medicine  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ozioma C.","family":"Okonkwo","sequence":"additional","affiliation":[{"name":"School of Medicine and Public Health, Wisconsin Alzheimer's Disease Research Center, University of Wisconsin\u2010Madison  Madison Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven P.","family":"Tam","sequence":"additional","affiliation":[{"name":"University of California, Irvine School of Medicine  Irvine California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. 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