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Linear and non\u2010linear correlations between CSF biomarkers were evaluated studying conditional independence relationships.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>CSF levels of inflammatory cytokines and neuronal\/glial markers were higher in ENC compared to controls, whereas the levels of amyloid\u2010related markers did not differ. Inflammatory markers were not associated with amyloid markers but exhibited a correlation with glial and neuronal markers in conditional independence analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>By an extensive CSF biomarkers analysis, this study showed that an acute neuroinflammation state, which is associated with glial activation and neuronal damage, does not influence amyloid homeostasis.<\/jats:p><\/jats:sec>","DOI":"10.1002\/alz.12554","type":"journal-article","created":{"date-parts":[[2022,1,27]],"date-time":"2022-01-27T07:13:19Z","timestamp":1643267599000},"page":"2167-2175","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Is amyloid involved in acute neuroinflammation? 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