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New initiatives aim to increase inclusion and engagement of commonly underincluded communities using digital, community\u2010engaged research strategies. New features include multilingual support and biofluid collection capabilities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>BHR includes\u00a0&gt;\u00a0100,000 participants. BHR has made over 259,000 referrals resulting in 25,997 participants enrolled in 30 aging and AD studies. In addition, 28,278 participants are coenrolled in BHR and other studies with data linkage among studies. Data have been shared with 28 investigators. Recent efforts have facilitated the enrollment and engagement of underincluded ethnocultural communities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>The major advantages of the BHR approach are scalability and accessibility. Challenges include compliance, retention, cohort diversity, and generalizability.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                    <jats:p>\n                      <jats:list list-type=\"bullet\">\n                        <jats:list-item>\n                          <jats:p>Brain Health Registry (BHR) is an online, longitudinal platform of\u00a0&gt;\u00a0100,000 members.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>BHR made\u00a0&gt;\u00a0259,000 referrals, which enrolled 25,997 participants in 32 studies.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>New efforts increased enrollment and engagement of underincluded communities in BHR.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>The major advantages of the BHR approach are scalability and accessibility.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>BHR provides a unique adjunct for clinical neuroscience research.<\/jats:p>\n                        <\/jats:list-item>\n                      <\/jats:list>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/alz.13077","type":"journal-article","created":{"date-parts":[[2023,3,25]],"date-time":"2023-03-25T15:50:57Z","timestamp":1679759457000},"page":"4935-4951","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["Brain health registry updates: An online longitudinal neuroscience platform"],"prefix":"10.1002","volume":"19","author":[{"given":"Michael W.","family":"Weiner","sequence":"first","affiliation":[{"name":"Northern California 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