{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T06:00:12Z","timestamp":1787896812114,"version":"build-2784847793"},"reference-count":66,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2023,7,10]],"date-time":"2023-07-10T00:00:00Z","timestamp":1688947200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000864","name":"Michael J. 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The Neuropsychiatric Inventory Questionnaire (NPI\u2010Q) was used to assess NPSs.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>NPSs were highly prevalent in Hispanic populations with neurodegenerative disease; approximately 34.3%, 56.1%, and 61.2% of the participants with parkinsonism, dementia, and PDD exhibited three or more NPSs, respectively. NPSs were the major contributor to caregiver burden.<\/jats:p><\/jats:sec><jats:sec><jats:title>DISCUSSION<\/jats:title><jats:p>Clinicians involved in the care of elderly populations should proactively screen for NPSs, especially in patients with parkinsonism, dementia, and PPD, and develop intervention plans to support families and caregivers.<\/jats:p><jats:sec><jats:title>Highlights<\/jats:title><jats:p><jats:list list-type=\"bullet\">\n<jats:list-item><jats:p>Neuropsychiatric symptoms (NPSs) are highly prevalent in Hispanic populations with neurodegenerative diseases.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>In healthy Hispanic populations, NPSs are predominantly mild and not clinically significant.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>The most common NPSs include depression, sleep disorders, irritability, and agitation.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>NPSs explain a substantial proportion of the variance in global caregiver burden.<\/jats:p><\/jats:list-item>\n<\/jats:list><\/jats:p><\/jats:sec><\/jats:sec>","DOI":"10.1002\/alz.13384","type":"journal-article","created":{"date-parts":[[2023,7,10]],"date-time":"2023-07-10T07:54:14Z","timestamp":1688975654000},"page":"5730-5741","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Prevalence and impact of neuropsychiatric symptoms in normal aging and neurodegenerative syndromes: A population\u2010based study from Latin America"],"prefix":"10.1002","volume":"19","author":[{"given":"Ana M.","family":"Rodriguez Salgado","sequence":"first","affiliation":[{"name":"Global Brain Health Institute University of San Francisco California San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isaac","family":"Acosta","sequence":"additional","affiliation":[{"name":"Laboratory of the Dementias National Institute of Neurology and Neurosurgery Mexico City 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