{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T23:15:58Z","timestamp":1784675758914,"version":"3.55.0"},"reference-count":42,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["NSFC\/72274170"],"award-info":[{"award-number":["NSFC\/72274170"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["NSFC\/ 82201733"],"award-info":[{"award-number":["NSFC\/ 82201733"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["alz-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Alzheimer's &amp;amp; Dementia"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>INTRODUCTION<\/jats:title><jats:p>We investigated the validity, feasibility, and effectiveness of a voice recognition\u2010based digital cognitive screener (DCS), for detecting dementia and mild cognitive impairment (MCI) in a large\u2010scale community of elderly participants.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS<\/jats:title><jats:p>Eligible participants completed demographic, cognitive, functional assessments and the DCS. Neuropsychological tests were used to assess domain\u2010specific and global cognition, while the diagnosis of MCI and dementia relied on the Clinical Dementia Rating Scale.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Among the\u00a011,186 participants, the DCS showed high completion rates (97.5%) and a short administration time (5.9 min) across gender, age, and education groups. The DCS demonstrated areas under the receiver operating characteristics curve (AUCs) of 0.95 and 0.83 for dementia and MCI detection, respectively, among 328 participants in the validation phase. Furthermore, the DCS resulted in time savings of 16.2% to 36.0% compared to the Mini\u2010Mental State Examination (MMSE) and Montral Cognitive Assessment (MoCA).<\/jats:p><\/jats:sec><jats:sec><jats:title>DISCUSSION<\/jats:title><jats:p>This study suggests that the DCS is an effective and efficient tool for dementia and MCI case\u2010finding in large\u2010scale cognitive screening.<\/jats:p><\/jats:sec><jats:sec><jats:title>Highlights<\/jats:title><jats:p><jats:list list-type=\"bullet\">\n<jats:list-item><jats:p>To our best knowledge, this is the first cognitive screening tool based on voice recognition and utilizing conversational AI that has been assessed in a large population of Chinese community\u2010dwelling elderly.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>With the upgrading of a new multimodal understanding model, the DCS can accurately assess participants' responses, including different Chinese dialects, and provide automatic scores.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>The DCS not only exhibited good discriminant ability in detecting dementia and MCI cases, it also demonstrated a high completion rate and efficient administration regardless of gender, age, and education differences.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>The DCS is economically efficient, scalable, and had a better screening efficacy compared to the MMSE or MoCA, for wider implementation.<\/jats:p><\/jats:list-item>\n<\/jats:list><\/jats:p><\/jats:sec>","DOI":"10.1002\/alz.13668","type":"journal-article","created":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T07:00:10Z","timestamp":1706770810000},"page":"2384-2396","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Validity, feasibility, and effectiveness of a voice\u2010recognition based digital cognitive screener for dementia and mild cognitive impairment in community\u2010dwelling older Chinese adults: A large\u2010scale implementation study"],"prefix":"10.1002","volume":"20","author":[{"given":"Xuhao","family":"Zhao","sequence":"first","affiliation":[{"name":"School of Public Health, The Second Affiliated Hospital of School of Medicine Zhejiang University Hangzhou Zhejiang P. 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China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruofei","family":"Hu","sequence":"additional","affiliation":[{"name":"DAMO Academy, Alibaba Group  Hangzhou Zhejiang P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Yan","sequence":"additional","affiliation":[{"name":"DAMO Academy, Alibaba Group  Hangzhou Zhejiang P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Pharmacology Yong Loo Lin School of Medicine Memory, Ageing, and Cognition Centre (MACC) National University of Singapore  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xifeng","family":"Wu","sequence":"additional","affiliation":[{"name":"School of Public Health, The Second Affiliated Hospital of School of Medicine Zhejiang University Hangzhou Zhejiang P. R. 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China"},{"name":"Department of Pharmacology Yong Loo Lin School of Medicine Memory, Ageing, and Cognition Centre (MACC) National University of Singapore  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,2]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(18)30499-X"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(19)30290-X"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/alz.12901"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0263077"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2019.22258"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-2667(20)30185-7"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2666-7568(22)00219-7"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30367-6"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2022.104030"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.14283\/jpad.2020.19"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/geroni\/igy038"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2021.101506"},{"issue":"1","key":"e_1_2_9_14_1","article-title":"Current advances in digital cognitive assessment for preclinical Alzheimer's disease","volume":"13","author":"Ohman F","year":"2021","journal-title":"Alzheimers Dement"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2022.899729"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/alz.12721"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.329.7476.1233"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.2165\/00019053-199813030-00002"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.4103\/2452-2473.357348"},{"key":"e_1_2_9_20_1","first-page":"5099","article-title":"Cross\u2010modal contrastive learning for speech translation","author":"Ye R","year":"2022","journal-title":"NAACL"},{"key":"e_1_2_9_21_1","first-page":"7241","article-title":"mPLUG: effective and efficient vision\u2010language learning by cross\u2010modal skip\u2010connections","author":"Li C","year":"2022","journal-title":"EMNLP"},{"key":"e_1_2_9_22_1","first-page":"2426","article-title":"Unsupervised cross\u2010lingual representation learning for speech recognition","author":"Conneau A","year":"2021","journal-title":"Interspeech"},{"key":"e_1_2_9_23_1","unstructured":"Common Voice Web site. 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