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Fisher's exact tests compared EOAD and LOAD on the presence and severity of NPSs. Multiple logistic regression models included an <jats:italic>age*diagnosis<\/jats:italic> interaction to examine age effects.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Presence (<jats:italic>p<\/jats:italic>s\u00a0&lt;\u00a00.0001) and severity (<jats:italic>p<\/jats:italic>s\u00a0&lt;\u00a00.05) of NPS were greater in EOAD than in LOAD. However, after adjusting for base rates in NPS in CU individuals (age effects), only elation and eating behaviors were more frequent in EOAD (<jats:italic>p<\/jats:italic>s\u00a0&lt;\u00a00.05) and nighttime behaviors more frequent and severe in LOAD (<jats:italic>p<\/jats:italic>s\u00a0&lt;\u00a00.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>DISCUSSION<\/jats:title><jats:p>Few NPSs were specific to the EOAD versus LOAD. 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