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Dementia"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>We sought to characterize the cognitive profile among individuals with mild cognitive impairment with Lewy bodies (MCI\u2010LB) to help guide future clinical criteria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>Systematic review and meta\u2010analysis included MCI\u2010LB studies with cognitive data from PubMed, Embase, Web of Science, and PsycINFO (January 1990 to March 2023). MCI\u2010LB scores were compared to controls, MCI due to Alzheimer's disease (MCI\u2010AD), and dementia with Lewy bodies (DLB) groups with random\u2010effects models.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>\n                      We included 26 studies and 2823 participants. Across all domains, the MCI\u2010LB group performed worse than controls and better than DLB. Compared to MCI\u2010AD, the MCI\u2010LB group performed worse in attention\/processing speed (\n                      <jats:italic>g\u00a0<\/jats:italic>\n                      =\u00a0\u20130.24, 95% confidence interval [CI]: \u20130.35, \u20130.12), attention\/executive (\n                      <jats:italic>g\u00a0<\/jats:italic>\n                      =\u00a0\u20130.42, 95% CI: \u20130.56, \u20130.28); better in verbal immediate recall (\n                      <jats:italic>g\u00a0<\/jats:italic>\n                      =\u00a00.37; 95% CI: 0.15, 0.59) and delayed memory (\n                      <jats:italic>g\u00a0<\/jats:italic>\n                      =\u00a00.40; 95% CI: 0.22, 0.58).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DISCUSSION<\/jats:title>\n                    <jats:p>The cognitive profiles in MCI\u2010LB and MCI\u2010AD are consistent with established profiles in DLB and AD. Neuropsychological assessment may be helpful in differential diagnosis, even in early disease states.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                    <jats:p>\n                      <jats:list list-type=\"bullet\">\n                        <jats:list-item>\n                          <jats:p>We performed a systematic review and meta\u2010analysis for cognition in mild cognitive impairment with Lewy bodies (MCI\u2010LB).<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>Compared to MCI due to Alzheimer's disease (MCI\u2010AD), MCI\u2010LB had worse attention, executive function, and processing speed.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>Compared to MCI\u2010AD, MCI\u2010LB had better verbal immediate and delayed recall.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>The MCI\u2010LB group was worse on all cognitive domains than controls, and better than dementia with Lewy bodies.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>Studies used different tests and there is a need for global efforts for harmonization.<\/jats:p>\n                        <\/jats:list-item>\n                      <\/jats:list>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/alz.14450","type":"journal-article","created":{"date-parts":[[2025,1,10]],"date-time":"2025-01-10T07:01:28Z","timestamp":1736492488000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Neuropsychological test performance in mild cognitive impairment with Lewy bodies: A systematic review and meta\u2010analysis"],"prefix":"10.1002","volume":"21","author":[{"given":"Kathryn A.","family":"Wyman\u2010Chick","sequence":"first","affiliation":[{"name":"Struthers Parkinson's Center Department of Neurology HealthPartners\/Park Nicollet  Golden Valley Minnesota USA"},{"name":"HealthPartners Institute  Bloomington Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6875-4242","authenticated-orcid":false,"given":"Ece","family":"Bayram","sequence":"additional","affiliation":[{"name":"Movement Disorders Center Department of Neurology University of Colorado Anschutz  Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Gravett","sequence":"additional","affiliation":[{"name":"Theme Women's Health and Allied Health Professionals Karolinska University Hospital  Stockholm Sweden"},{"name":"Department of Neurobiology Care Sciences and Society Karolinska Institutet  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrizia","family":"D'Antonio","sequence":"additional","affiliation":[{"name":"Department of Human Neurosciences Sapienza University of Rome  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federico","family":"Rodriguez\u2010Porcel","sequence":"additional","affiliation":[{"name":"Department of Neurology Medical University of South Carolina  Charleston South Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph P. 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