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This trend is also evident in Latin America, where life expectancy is improving, though at varying rates across countries and regions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>Partnering with the Neurosciences Group of Antioquia (GNA), we launched a Colombian study on resilience in families with autosomal dominant Alzheimer's disease and the oldest\u2010old population. Over the past 2 years, the project has expanded to include participants from Peru, Chile, and Costa Rica.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>This research led to the first symposium on Brain Resilience and Healthy Longevity, held in Medell\u00edn, Colombia, in August 2024.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DISCUSSION<\/jats:title>\n                    <jats:p>The article summarizes key discussions from the symposium, highlighting the most promising opportunities for brain resilience and prevention research in the region and offering recommendations for future research to promote healthy aging and dementia\u2010free communities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                    <jats:p>\n                      <jats:list list-type=\"bullet\">\n                        <jats:list-item>\n                          <jats:p>Uncovering the genetic and physiological drivers of cognitive resilience, neurodegeneration resistance, and healthy longevity is essential for maintaining brain function as we age.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>\u201cSuperagers\u201d and cognitively resilient individuals from Latin American families with Alzheimer's disease offer valuable insights into brain protection mechanisms.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>Studying the interplay of socio\u2010environmental and genetic factors in the oldest\u2010old is key to understanding healthy longevity and improving dementia prevention.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>The inaugural Brain Resilience and Healthy Longevity Symposium highlights the need for global collaboration to uncover factors that drive cognitive resilience and healthy aging in Latin America, advancing dementia prevention.<\/jats:p>\n                        <\/jats:list-item>\n                      <\/jats:list>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/alz.70037","type":"journal-article","created":{"date-parts":[[2025,3,29]],"date-time":"2025-03-29T23:35:55Z","timestamp":1743291355000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Driving research on successful aging and neuroprotection in Latin America: Insights from the inaugural symposium on brain resilience and healthy longevity"],"prefix":"10.1002","volume":"21","author":[{"given":"Yakeel T.","family":"Quiroz","sequence":"first","affiliation":[{"name":"Harvard Medical School Massachusetts General Hospital  Boston Massachusetts USA"},{"name":"Boston University Department of Psychological and Brain Sciences  Boston Massachusetts USA"},{"name":"Grupo de Neurociencias de Antioquia, Facultad de Medicina Universidad de Antioquia, Calle 62 # 52 \u201059, Sede de Investigaci\u00f3n Universitaria \u2010 SIU  Medell\u00edn Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Aguill\u00f3n","sequence":"additional","affiliation":[{"name":"Grupo de Neurociencias de Antioquia, Facultad de Medicina Universidad de Antioquia, Calle 62 # 52 \u201059, Sede de Investigaci\u00f3n Universitaria \u2010 SIU  Medell\u00edn Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Arboleda\u2010Velasquez","sequence":"additional","affiliation":[{"name":"Schepens Eye Research Institute, Mass Eye and Ear, Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yamile","family":"Bocanegra","sequence":"additional","affiliation":[{"name":"Grupo de Neurociencias de Antioquia, Facultad de Medicina Universidad de Antioquia, Calle 62 # 52 \u201059, Sede de Investigaci\u00f3n Universitaria \u2010 SIU  Medell\u00edn Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gloria Patricia","family":"Cardona\u2010G\u00f3mez","sequence":"additional","affiliation":[{"name":"Grupo de Neurociencias de Antioquia, Facultad de Medicina Universidad de Antioquia, Calle 62 # 52 \u201059, Sede de Investigaci\u00f3n Universitaria \u2010 SIU  Medell\u00edn Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria M.","family":"Corrada","sequence":"additional","affiliation":[{"name":"Department of Neurology and Department of Epidemiology &amp; 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