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The Tau2024 Global Conference, hosted by the Alzheimer's Association, CurePSP, and Rainwater Charitable Foundation, showcased these efforts by bringing together researchers and experts worldwide to discuss the latest advancements in tau research. The conference aimed to attract talent and funding to study tauopathies, particularly among early\u2010career researchers, and to foster interdisciplinary alignment and collaboration around challenges in tau research. In this manuscript, we summarize proceedings of the Tau2024 Global Conference, covering a wide range of topics, including lived experiences of individuals with genetic forms of tauopathies, global perspectives on tauopathies, and molecular mechanisms, brain microenvironments, biomarker developments, clinical trials, and therapeutic approaches to tauopathies. Through international, collaborative efforts, innovative research, and a commitment to inclusivity, researchers worldwide have demonstrated transformative breakthroughs toward diagnosing, treating, and, ultimately, preventing tau\u2010related diseases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                    <jats:p>\n                      <jats:list list-type=\"bullet\">\n                        <jats:list-item>\n                          <jats:p>The Tau2024 Global Conference presented updates and advances in tau research.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>Blood\u2010based biomarkers offer specificity and longitudinal monitoring capabilities.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>There are a range of targetable mechanisms in the cascade of pathogenesis.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>International collaboration is vital to address disparities in tauopathies.<\/jats:p>\n                        <\/jats:list-item>\n                      <\/jats:list>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/alz.70078","type":"journal-article","created":{"date-parts":[[2025,5,29]],"date-time":"2025-05-29T03:15:42Z","timestamp":1748488542000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Insights into pathophysiology, biomarkers, and therapeutics in tauopathies: Proceedings of the Tau2024 Global Conference"],"prefix":"10.1002","volume":"21","author":[{"given":"Bess","family":"Frost","sequence":"first","affiliation":[{"name":"Center for Alzheimer's Disease Research, Department of Molecular Biology, Cell Biology and Biochemistry Brown University  Providence Rhode Island USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James B.","family":"Rowe","sequence":"additional","affiliation":[{"name":"Department of Clinical Neurosciences, MRC Cognition and Brain Sciences Unit, and Cambridge University Hospitals NHS Foundation Trust, Cambridge Biomedical Campus University of Cambridge  Cambridge UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rufus O.","family":"Akinyemi","sequence":"additional","affiliation":[{"name":"Neuroscience and Ageing Research Unit, Institute for Advanced Medical Research and Training, College of Medicine University of Ibadan  Ibadan Oyo State Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose F.","family":"Abisambra","sequence":"additional","affiliation":[{"name":"McKnight Brain Institute, Brain Injury, Rehabilitation, and Neuroresilience Center, Center for Translational Research in Neurodegenerative Disease, Fixel Institute, Department of Neuroscience University of Florida  Gainesville Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas J.","family":"Ashton","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Neurochemistry University of Gothenburg  Gothenburg Sweden"},{"name":"Banner Alzheimer's Institute and University of Arizona  Phoenix Arizona USA"},{"name":"Banner Sun Health Research Institute  Sun City Arizona USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Brendel","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine LMU University Hospital  Munich Germany"},{"name":"German Center for Neurodegenerative Diseases (DZNE)  Munich Germany"},{"name":"Munich Cluster for Systems Neurology (SyNergy)  Munich Germany"},{"name":"German Cancer Consortium (DKTK), partner site Munich, a partnership between DKFZ and Ludwig\u2010Maximilians\u2010Universit\u00e4t M\u00fcnchen (LMU)  Heidelberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luc","family":"Bu\u00e9e","sequence":"additional","affiliation":[{"name":"Inserm, CHU\u2010Lille, Lille Neuroscience &amp; Cognition University of Lille  Lille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Butler","sequence":"additional","affiliation":[{"name":"Neural Stem Cell Institute  Rensselaer New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria C.","family":"Carrillo","sequence":"additional","affiliation":[{"name":"Medical &amp; Scientific Relations Alzheimer's Association  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Physics and Astronomy, Department of Chemistry, and Alfred E. Mann Department of Biomedical Engineering University of Southern California  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire D.","family":"Clelland","sequence":"additional","affiliation":[{"name":"Weill Institute for Neurosciences University of California San Francisco  San Francisco California USA"},{"name":"Memory &amp; Aging Center University of California San Francisco  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah L.","family":"DeVos","sequence":"additional","affiliation":[{"name":"Cure.Bio  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristophe","family":"Diaz","sequence":"additional","affiliation":[{"name":"CurePSP, Inc  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca M.","family":"Edelmayer","sequence":"additional","affiliation":[{"name":"Medical &amp; Scientific Relations Alzheimer's Association  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fanny M.","family":"Elahi","sequence":"additional","affiliation":[{"name":"Departments of Neurology, Neuroscience, Pathology, Molecular and Cell\u2010Based Medicine Icahn School of Medicine at Mount Sinai  New York New York USA"},{"name":"James J. 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