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P\u2010tau181 impacted diagnostic confidence, AD\u2010related medication prescription, and follow\u2010on testing. Renal impairment was a common confounder.<\/jats:p>\n <\/jats:sec>\n \n CONCLUSIONS<\/jats:title>\n Implementation of BBMs was feasible and impactful in a memory clinic, especially in a diagnostically complex and diverse patient population, underscoring the need for additional data from real\u2010world settings.<\/jats:p>\n <\/jats:sec>\n \n Highlights<\/jats:title>\n \n \n \n Blood\u2010based biomarkers (BBMs) were quickly adopted and accelerated precision diagnosis in a large memory clinic.<\/jats:p>\n <\/jats:list-item>\n \n BBM use cases were diverse and included all stages\/types of AD and non\u2010AD syndromes.<\/jats:p>\n <\/jats:list-item>\n \n Plasma p\u2010tau has the potential to impact diagnostic certainty and clinical decision making.<\/jats:p>\n <\/jats:list-item>\n \n Diagnostic performance of p\u2010tau is reasonable, though renal function impacts overall accuracy.<\/jats:p>\n <\/jats:list-item>\n <\/jats:list>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/alz.70891","type":"journal-article","created":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T15:54:10Z","timestamp":1763049250000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Blood\u2010based Alzheimer's disease biomarkers in a behavioral neurology clinic: Real\u2010world implementation, clinical utility, and diagnostic performance"],"prefix":"10.1002","volume":"21","author":[{"given":"Igor","family":"Prufer Q C Araujo","sequence":"first","affiliation":[{"name":"Edward and Pearl Fein Memory and Aging Center Weill Institute for Neurosciences Department of Neurology University of California San Francisco San Francisco California US"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tara","family":"Ellingson","sequence":"additional","affiliation":[{"name":"Edward and Pearl Fein Memory and Aging Center Weill Institute for Neurosciences Department of Neurology 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