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Mediation analysis indicated that cognitive impairment accounted for \u224862%\u00a0of the association between sleep disorders and IADL difficulties, suggesting a substantial indirect association through cognitive function.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DISCUSSION<\/jats:title>\n                    <jats:p>Sleep disorders are strongly associated with cognitive impairment and functional limitations in AD. These findings highlight the potential clinical value of screening and managing sleep problems as part of comprehensive care strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/alz.71200","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T11:11:31Z","timestamp":1772968291000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Waking up to the truth: Associations between sleep disorders and multidomain functional outcomes in Alzheimer's disease"],"prefix":"10.1002","volume":"22","author":[{"given":"Chao","family":"Tang","sequence":"first","affiliation":[{"name":"Department of Neurology Affiliated Hospital of Guizhou Medical University  Guiyang Guizhou Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaxin","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Neurology Affiliated Hospital of Guizhou Medical 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