{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T22:24:08Z","timestamp":1789597448367,"version":"build-2803163510"},"reference-count":155,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T00:00:00Z","timestamp":1772409600000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100014808","name":"Fondation Vaincre Alzheimer","doi-asserted-by":"publisher","award":["FR\u201024024R\u2010Hay"],"award-info":[{"award-number":["FR\u201024024R\u2010Hay"]}],"id":[{"id":"10.13039\/100014808","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003750","name":"Association France Alzheimer","doi-asserted-by":"publisher","award":["PFA 2023 \u2010 #6389"],"award-info":[{"award-number":["PFA 2023 \u2010 #6389"]}],"id":[{"id":"10.13039\/501100003750","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["alz-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Alzheimer's &amp;amp; Dementia"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Alzheimer's disease (AD), the most common neurodegenerative disorder, is frequently accompanied by sleep disturbances. Alterations of sleep, in both quality and quantity, contribute to the progression of AD neuropathology. The thalamus, through its diverse nuclei, plays a central role in sleep regulation and sleep\u2010dependent memory consolidation, making it a relevant structure to investigate sleep disturbances associated with AD. Structural studies reveal that AD\u2010related changes emerge early within the thalamus: Higher\u2010order nuclei show atrophy, degeneration, and tau and A\u03b2 accumulation. AD is also associated with functional and connectivity impairments involving the thalamus. Moreover, the thalamus plays a major role in generating, propagating, and synchronizing sleep oscillations, which are crucial for sleep\u2010dependent memory, and alterations of the thalamus are linked with cognitive decline in AD. Thus, here we highlight this structure as a promising therapeutic target for restoring sleep physiology and cognitive function in AD.<\/jats:p>","DOI":"10.1002\/alz.71242","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T17:03:08Z","timestamp":1772989388000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Implication of the thalamus in sleep alterations observed in Alzheimer's disease"],"prefix":"10.1002","volume":"22","author":[{"given":"Carla","family":"Burnet\u2010Merlin","sequence":"first","affiliation":[{"name":"Forgetting Processes and Cortical Dynamics Lyon Neuroscience Research Center INSERM U1028\u2010CNRS UMR5292 Universit\u00e9 Claude Bernard\u2010Lyon 1  Lyon, Auvergne\u2010Rh\u00f4ne\u2010Alpes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y. Audrey","family":"Hay","sequence":"additional","affiliation":[{"name":"Forgetting Processes and Cortical Dynamics Lyon Neuroscience Research Center INSERM U1028\u2010CNRS UMR5292 Universit\u00e9 Claude Bernard\u2010Lyon 1  Lyon, Auvergne\u2010Rh\u00f4ne\u2010Alpes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6316-1624","authenticated-orcid":false,"given":"Aur\u00e9lie","family":"Br\u00e9cier","sequence":"additional","affiliation":[{"name":"Forgetting Processes and Cortical Dynamics Lyon Neuroscience Research Center INSERM U1028\u2010CNRS UMR5292 Universit\u00e9 Claude Bernard\u2010Lyon 1  Lyon, Auvergne\u2010Rh\u00f4ne\u2010Alpes France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,2]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002093-200210000-00001"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/emm.2014.121"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1523\/ENEURO.0093-20.2020"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41398-022-01897-y"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI169131"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/WNR.0b013e32830867c4"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/8376108"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1241224"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2017.06.025"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0144720"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/braincomms\/fcab101"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-210173"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2013.2334"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1721694115"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2021.03.015"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.16.8854"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2018.10.024"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn.2017.151"},{"key":"e_1_2_8_20_1","volume-title":"Exploring the Thalamus","author":"Sherman SM","year":"2001"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41593-021-00996-1"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.conb.2007.07.003"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2015.01.014"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(01)00582-7"},{"key":"e_1_2_8_25_1","volume-title":"The Thalamus","author":"Jones E","year":"2007"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.0040382"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.10137"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2015.03.001"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.903370102"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainresbull.2006.12.002"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/0013-4694(49)90219-9"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1417.029"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnbeh.2022.964644"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.90826.3"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0771-13.2013"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature14396"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.3917"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.4269"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.22559"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.conb.2018.08.002"},{"key":"e_1_2_8_41_1","first-page":"1","article-title":"The limbic system in Alzheimer's disease. A neuropathologic investigation","volume":"85","author":"Hopper MW","year":"1976","journal-title":"Am J Pathol"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2013.07.001"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pneurobio.2005.01.001"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cortex.2013.12.005"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awt065"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awq310"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-010-5872-1"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-210173"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.4306\/pi.2016.13.5.504"},{"key":"e_1_2_8_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2017.01.009"},{"key":"e_1_2_8_51_1","doi-asserted-by":"publisher","DOI":"10.1177\/13872877251390386"},{"key":"e_1_2_8_52_1","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-150639"},{"key":"e_1_2_8_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dadm.2019.08.001"},{"key":"e_1_2_8_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2022.03.034"},{"key":"e_1_2_8_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2014.05.004"},{"key":"e_1_2_8_56_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.24401"},{"issue":"3","key":"e_1_2_8_57_1","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1093\/brain\/114.3.1363","article-title":"Nerve cell loss in the thalamus in Alzheimer's disease and Parkinson's disease","volume":"114","author":"Xuereb JH","year":"1991","journal-title":"Brain J Neurol"},{"key":"e_1_2_8_58_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.57.9.1669"},{"key":"e_1_2_8_59_1","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-201583"},{"key":"e_1_2_8_60_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00305867"},{"key":"e_1_2_8_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(87)90123-0"},{"key":"e_1_2_8_62_1","doi-asserted-by":"publisher","DOI":"10.1111\/bpa.12289"},{"key":"e_1_2_8_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2010.12.044"},{"key":"e_1_2_8_64_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhu246"},{"key":"e_1_2_8_65_1","doi-asserted-by":"publisher","DOI":"10.2174\/15672050113109990146"},{"key":"e_1_2_8_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2022.06.006"},{"key":"e_1_2_8_67_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41593-017-0020-1"},{"key":"e_1_2_8_68_1","doi-asserted-by":"publisher","DOI":"10.3390\/biology14040395"},{"key":"e_1_2_8_69_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13195-020-00752-w"},{"key":"e_1_2_8_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropsychologia.2007.11.030"},{"key":"e_1_2_8_71_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.abh4284"},{"key":"e_1_2_8_72_1","doi-asserted-by":"publisher","DOI":"10.1177\/13872877241295401"},{"key":"e_1_2_8_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2016.04.016"},{"key":"e_1_2_8_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2019.07.019"},{"key":"e_1_2_8_75_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.neuro.20.1.185"},{"key":"e_1_2_8_76_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.3035"},{"key":"e_1_2_8_77_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pneurobio.2013.08.006"},{"key":"e_1_2_8_78_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1996.76.3.1367"},{"key":"e_1_2_8_79_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.8235588"},{"key":"e_1_2_8_80_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.15-05-03526.1995"},{"key":"e_1_2_8_81_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/30.12.1643"},{"key":"e_1_2_8_82_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2005.05.002"},{"key":"e_1_2_8_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainresbull.2007.05.001"},{"key":"e_1_2_8_84_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainresbull.2022.07.002"},{"key":"e_1_2_8_85_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aau6550"},{"key":"e_1_2_8_86_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.4035"},{"key":"e_1_2_8_87_1","doi-asserted-by":"publisher","DOI":"10.5665\/sleep.6240"},{"key":"e_1_2_8_88_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2023.106378"},{"key":"e_1_2_8_89_1","doi-asserted-by":"publisher","DOI":"10.1002\/alz.70247"},{"key":"e_1_2_8_90_1","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-2010-100879"},{"key":"e_1_2_8_91_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)61223-0"},{"key":"e_1_2_8_92_1","doi-asserted-by":"publisher","DOI":"10.1038\/79848"},{"key":"e_1_2_8_93_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3169-13.2013"},{"key":"e_1_2_8_94_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2021.06.030"},{"key":"e_1_2_8_95_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1990.sp018331"},{"key":"e_1_2_8_96_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.11-10-03200.1991"},{"key":"e_1_2_8_97_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.2445"},{"key":"e_1_2_8_98_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-29852-x"},{"key":"e_1_2_8_99_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4460-13.2014"},{"key":"e_1_2_8_100_1","doi-asserted-by":"publisher","DOI":"10.1523\/ENEURO.0365-19.2019"},{"key":"e_1_2_8_101_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2604-11.2011"},{"key":"e_1_2_8_102_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0158-24.2024"},{"key":"e_1_2_8_103_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-017-00735-w"},{"key":"e_1_2_8_104_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2149-05.2005"},{"key":"e_1_2_8_105_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2018.01.087"},{"key":"e_1_2_8_106_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/27.7.1479"},{"key":"e_1_2_8_107_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2016.06.044"},{"key":"e_1_2_8_108_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1987.57.1.260"},{"key":"e_1_2_8_109_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00018.2002"},{"key":"e_1_2_8_110_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4522(96)00393-4"},{"key":"e_1_2_8_111_1","doi-asserted-by":"publisher","DOI":"10.1053\/smrv.2002.0252"},{"key":"e_1_2_8_112_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2016.01.061"},{"key":"e_1_2_8_113_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3130-14.2015"},{"key":"e_1_2_8_114_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2016.04.009"},{"key":"e_1_2_8_115_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature20587"},{"key":"e_1_2_8_116_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-56582-w"},{"key":"e_1_2_8_117_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep22728"},{"key":"e_1_2_8_118_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2014.282889"},{"key":"e_1_2_8_119_1","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.22488"},{"key":"e_1_2_8_120_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0867-14.2014"},{"key":"e_1_2_8_121_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00014.2006"},{"key":"e_1_2_8_122_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3058-17.2018"},{"key":"e_1_2_8_123_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2014.06.023"},{"key":"e_1_2_8_124_1","article-title":"High\u2010frequency oscillations in epileptic and non\u2010epileptic Alzheimer's disease patients and the differential effect of levetiracetam on the oscillations","volume":"7","author":"Shandilya MCV","year":"2025","journal-title":"Brain Commun"},{"key":"e_1_2_8_125_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn2762"},{"key":"e_1_2_8_126_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2017.05.054"},{"key":"e_1_2_8_127_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.22733"},{"key":"e_1_2_8_128_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-8993(00)03013-4"},{"key":"e_1_2_8_129_1","doi-asserted-by":"publisher","DOI":"10.1002\/syn.10279"},{"key":"e_1_2_8_130_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00429-013-0543-5"},{"key":"e_1_2_8_131_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2006.10.023"},{"key":"e_1_2_8_132_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(00)80629-7"},{"key":"e_1_2_8_133_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41593-019-0467-3"},{"key":"e_1_2_8_134_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.4119"},{"key":"e_1_2_8_135_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41593-023-01381-w"},{"key":"e_1_2_8_136_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2020.04.087"},{"key":"e_1_2_8_137_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-41851-5"},{"key":"e_1_2_8_138_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.2384"},{"key":"e_1_2_8_139_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2017.11.020"},{"key":"e_1_2_8_140_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-32840-w"},{"key":"e_1_2_8_141_1","doi-asserted-by":"publisher","DOI":"10.1111\/ejn.15853"},{"key":"e_1_2_8_142_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2021.02.025"},{"key":"e_1_2_8_143_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-neuro-061010-113817"},{"key":"e_1_2_8_144_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2016.01.040"},{"key":"e_1_2_8_145_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0170275"},{"key":"e_1_2_8_146_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature05278"},{"key":"e_1_2_8_147_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0260-17.2017"},{"key":"e_1_2_8_148_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2024.1519225"},{"key":"e_1_2_8_149_1","doi-asserted-by":"publisher","DOI":"10.5665\/sleep.2954"},{"key":"e_1_2_8_150_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-42721-5"},{"key":"e_1_2_8_151_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00429-020-02033-6"},{"key":"e_1_2_8_152_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.f.324"},{"key":"e_1_2_8_153_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-pharmtox-010814-124803"},{"key":"e_1_2_8_154_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0409644102"},{"key":"e_1_2_8_155_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1105115108"},{"key":"e_1_2_8_156_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00858.2015"}],"container-title":["Alzheimer's &amp; Dementia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/alz-journals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/alz.71242","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/alz-journals.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/alz.71242","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/alz-journals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/alz.71242","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T09:11:29Z","timestamp":1780045889000},"score":1,"resource":{"primary":{"URL":"https:\/\/alz-journals.onlinelibrary.wiley.com\/doi\/10.1002\/alz.71242"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":155,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1002\/alz.71242"],"URL":"https:\/\/doi.org\/10.1002\/alz.71242","archive":["Portico"],"relation":{},"ISSN":["1552-5260","1552-5279"],"issn-type":[{"value":"1552-5260","type":"print"},{"value":"1552-5279","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"2025-12-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-01","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-02","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e71242"}}