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Elevated switching rates were strongly correlated with A\u03b2 and tau burden in dorsal attention network and sensorimotor network, as well as with cognitive severity. Importantly, the interaction between network switching rate and A\u03b2 burden synergistically contributed to accelerated tau accumulation in Braak stage III to V regions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DISCUSSION<\/jats:title>\n                    <jats:p>These findings support the framework that increased network switching may amplify A\u03b2\u2010related tau load and cognitive deterioration in Alzheimer's disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/alz.71354","type":"journal-article","created":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T09:06:47Z","timestamp":1776157607000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Elevation in network dynamics amplifies amyloid\u2010dependent tau 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