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We identified key gaps and priorities for incorporating physical environment measures into population\u2010based research, with an emphasis on geospatial data that can be applied in large cohorts and administrative datasets.\u00a0The Gateway Exposome Coordinating Center (GECC) synthesized input from six town halls, a 4\u2010day expert workshop, and the literature to build consensus on priority physical environment exposures and a roadmap for advancing exposure data.\u00a0We also identified four methodological imperatives: developing pathway\u2010relevant metrics, addressing temporality, incorporating behavior into exposure estimation, and integrating co\u2010occurring exposures.\u00a0Advancing guidance and exposure metrics in these areas can support prevention\u2010oriented, policy\u2010relevant research and improve understanding of how physical environments influence brain health.<\/jats:p>\n                  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