{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T22:21:35Z","timestamp":1791411695048,"version":"4.3.3"},"reference-count":14,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T00:00:00Z","timestamp":1782259200000},"content-version":"vor","delay-in-days":23,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["#U01AG086827"],"award-info":[{"award-number":["#U01AG086827"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["alz-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Alzheimer's &amp; Dementia"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>INTRODUCTION<\/jats:title>\n                    <jats:p>Addressing dementia's substantial economic burden on individuals, families, health systems, governments, and payers, requires integrating national data and advanced analytic methods.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>We described data sources, measures, and simulation methods of a dynamic microsimulation model developed for quantifying dementia costs in the United States and for assessing impact of innovation and change over time. Model internal validation was assessed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>Using nationally representative Health and Retirement Study data on adults over age 50, Medicare and other national data, we produced estimates of individual\u2010level health and economic outcomes over time. Estimates and simulation enabled measurement of population\u2010level dementia prevalence, medical and long\u2010term care costs, unpaid caregiving valuation, quality\u2010of\u2010life, and earnings for persons living with dementia and care partners. Counterfactual scenarios quantified dementia\u2010related quality\u2010of\u2010life and earnings losses. Simulated outcomes aligned with observed data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>Transparent methods support replication, extension, and informed use of dementia cost estimates in research and policy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/alz.71549","type":"journal-article","created":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T11:01:35Z","timestamp":1782298895000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A dynamic microsimulation method for estimating dementia costs in the United States"],"prefix":"10.1002","volume":"22","author":[{"given":"Bryan","family":"Tysinger","sequence":"first","affiliation":[{"name":"Leonard D. Schaeffer Institute for Public Policy and Government Service University of Southern California Los Angeles California USA"},{"name":"Sol Price School of Public Policy University of Southern California  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanke","family":"Heun\u2010Johnson","sequence":"additional","affiliation":[{"name":"Leonard D. Schaeffer Institute for Public Policy and Government Service University of Southern California Los Angeles California USA"},{"name":"Sol Price School of Public Policy University of Southern California  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duncan","family":"Leaf","sequence":"additional","affiliation":[{"name":"Leonard D. Schaeffer Institute for Public Policy and Government Service University of Southern California Los Angeles California USA"},{"name":"Sol Price School of Public Policy University of Southern California  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johanna","family":"Thunell","sequence":"additional","affiliation":[{"name":"Leonard D. Schaeffer Institute for Public Policy and Government Service University of Southern California Los Angeles California USA"},{"name":"Sol Price School of Public Policy University of Southern California  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dana","family":"Goldman","sequence":"additional","affiliation":[{"name":"Leonard D. Schaeffer Institute for Public Policy and Government Service University of Southern California Los Angeles California USA"},{"name":"Sol Price School of Public Policy University of Southern California  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Zissimopoulos","sequence":"additional","affiliation":[{"name":"Leonard D. Schaeffer Institute for Public Policy and Government Service University of Southern California Los Angeles California USA"},{"name":"Sol Price School of Public Policy University of Southern California  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,24]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1515\/fhep\u20102014\u20100013"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41514\u2010024\u201000136\u20106"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsa1204629"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/hec.4169"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0274417"},{"key":"e_1_2_10_7_1","unstructured":"Administration SS.The 2010 Annual Report of the Board of Trustees of the Federal Old\u2010Age and Survivors Insurance and Federal Disability Insurance Trust Funds.2010."},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/1536867X1101100202"},{"key":"e_1_2_10_9_1","unstructured":"Data from: RAND HRS Longitudinal File. Santa Monica CA.2025. doi:https:\/\/www.rand.org\/health\/surveys\/hrs\/hrs\u2010data.html"},{"key":"e_1_2_10_10_1","doi-asserted-by":"crossref","unstructured":"OfstedalMB FisherGG HerzogAR.Documentation of cognitive functioning measures in the health and retirement study.Ann Arbor Michigan:University of Michigan;2005.","DOI":"10.7826\/ISR-UM.06.585031.001.05.0010.2005"},{"key":"e_1_2_10_11_1","unstructured":"LangaKM.Langa\u2010weir classification of cognitive function (1995\u20102020).Survey Research Center Institute for Social Research University of Michigan;2023. doi:https:\/\/hrsdata isr umich edu\/sites\/default\/files\/documentation\/data\u2010descriptions\/1680034270\/Data_Description_Langa_Weir_Classifications2020pdf"},{"key":"e_1_2_10_12_1","unstructured":"GenworthC.Calculate the cost of long\u2010term care near you. doi:https:\/\/www.carescout.com\/cost\u2010of\u2010care"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.18570"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.3109\/07853890109002092"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1257\/aer.104.5.230"}],"container-title":["Alzheimer's &amp; Dementia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/alz-journals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/alz.71549","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/alz-journals.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/alz.71549","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/alz-journals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/alz.71549","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T09:47:23Z","timestamp":1783244843000},"score":1,"resource":{"primary":{"URL":"https:\/\/alz-journals.onlinelibrary.wiley.com\/doi\/10.1002\/alz.71549"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":14,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["10.1002\/alz.71549"],"URL":"https:\/\/doi.org\/10.1002\/alz.71549","archive":["Portico"],"relation":{},"ISSN":["1552-5260","1552-5279"],"issn-type":[{"value":"1552-5260","type":"print"},{"value":"1552-5279","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"2026-02-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e71549"}}