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OSA status was determined by self\u2010report. Cognition was assessed using the Cogstate Brief Battery, and dementia risk using the Cardiovascular Risk Factors, Ageing, and Incidence of Dementia (CAIDE) score.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>\n                      Participants with OSA demonstrated poorer memory than those without OSA, although this association was attenuated after adjusting for vascular risk.\u00a0Individuals with OSA (with or without\n                      <jats:italic>APOE<\/jats:italic>\n                      \u03b54) had significantly higher CAIDE scores than those with neither risk factor.\n                      <jats:italic>APOE<\/jats:italic>\n                      \u03b54 did not moderate OSA\u2010cognition associations.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DISCUSSION<\/jats:title>\n                    <jats:p>\n                      OSA may be associated with poorer memory and greater dementia risk,\u00a0irrespective of\n                      <jats:italic>APOE<\/jats:italic>\n                      \u03b54 carriage. These findings highlight the need for early OSA screening to identify individuals at elevated dementia risk.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/alz.71553","type":"journal-article","created":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T11:00:10Z","timestamp":1782730810000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Associations of self\u2010reported obstructive sleep apnea with cognition and dementia risk in cognitively unimpaired middle\u2010aged adults"],"prefix":"10.1002","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5334-8535","authenticated-orcid":false,"given":"Gabriel T.","family":"Abdelmessih","sequence":"first","affiliation":[{"name":"Turner Institute for Brain and Mental Health School of Psychological Sciences Monash University  Clayton Victoria 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