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We estimated its association with dementia risk among Chinese, Japanese, Filipino, and non\u2010Latino White older adults in California.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>\n                      This longitudinal study included 1078 Chinese, 843 Japanese, 583 Filipino, and 43,821 non\u2010Latino White participants from the Genetic Epidemiology Research in Adult Health and Aging cohort (mean baseline age\u00a0=\u00a070 years). Dementia was identified using electronic health records. We estimated effects of\n                      <jats:italic>APOE\u2010\u03b54<\/jats:italic>\n                      carriership on dementia risk using pooled logistic regression.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>\n                      <jats:italic>APOE\u2010\u03b54<\/jats:italic>\n                      carriership prevalence ranged from 14% among Filipino to 25% among non\u2010Latino White participants.\n                      <jats:italic>APOE\u2010\u03b54<\/jats:italic>\n                      carriership was associated with higher dementia risk across groups; 10\u2010year risk ratios (95% confidence interval [CI]) ranged from 1.59 (0.66\u20133.10) among Filipino to 1.96 (1.36\u20132.78) among Japanese participants.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DISCUSSION<\/jats:title>\n                    <jats:p>\n                      Despite differences in prevalence of\n                      <jats:italic>APOE\u2010\u03b54<\/jats:italic>\n                      , its association with dementia risk was similar across Chinese, Japanese, Filipino, and non\u2010Latino White participants.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/alz.71615","type":"journal-article","created":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T06:50:55Z","timestamp":1783666255000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["<i>APOE\u2010\u03b54<\/i>\n                    carriership and dementia risk over 10 years among Asian American and White older adults"],"prefix":"10.1002","volume":"22","author":[{"given":"Yingyan","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Epidemiology, Fielding School of Public Health University of California, Los Angeles  Los Angeles California USA"},{"name":"Department of Epidemiology Boston University School of Public Health  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. 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