{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T04:05:47Z","timestamp":1785297947457,"version":"3.55.0"},"reference-count":22,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T00:00:00Z","timestamp":1783209600000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["MC_UU_00030\/14"],"award-info":[{"award-number":["MC_UU_00030\/14"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["MR\/T033371\/1"],"award-info":[{"award-number":["MR\/T033371\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["220258"],"award-info":[{"award-number":["220258"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018956","name":"NIHR Cambridge Biomedical Research Centre","doi-asserted-by":"publisher","award":["NIHR203312"],"award-info":[{"award-number":["NIHR203312"]}],"id":[{"id":"10.13039\/501100018956","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["alz-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Alzheimer's &amp; Dementia"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The Dame Barbara Windsor Dementia Goals Programme was launched by the UK Government to accelerate the development and delivery of new treatments for dementia. We present the recommendations from the Scientific Advisory Board, to enable timely access to therapies for the wider population, reducing health system burden while improving patient outcomes. The recommendations focus on three areas: (i) establishing a new dynamic national patient registry for clinical trial recruitment; (ii) the use of biomarkers to improve early and accurate diagnosis; and (iii) a framework for end\u2010to\u2010end implementation across the landscape of healthcare, research and regulators. A\u00a0\n                    <jats:italic>Brain Aging Registry for Biomarkers, Access to trials, Research and Adoption<\/jats:italic>\n                    \u00a0would support recruitment, monitoring, and personalized care. Embedding digital and biomarker innovations into routine care would improve personalized and equitable dementia services, with earlier diagnosis and more effective prevention. Robust patient and public involvement is required, to ensure transparency, trustworthiness, and meaningful participation.\n                  <\/jats:p>","DOI":"10.1002\/alz.71621","type":"journal-article","created":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T09:27:24Z","timestamp":1783243644000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Breaking barriers: Enhancing access to dementia clinical trials in the United Kingdom\u2014Insights from the Scientific Advisory Board of the Dame Barbara Windsor Dementia Goals Programme"],"prefix":"10.1002","volume":"22","author":[{"given":"Ruth M.","family":"McKernan","sequence":"first","affiliation":[{"name":"Chair of the Scientific Advisory Board of the Dementia Goals Programme Operating Partner of SV Health Investors  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7216-8679","authenticated-orcid":false,"given":"James B.","family":"Rowe","sequence":"additional","affiliation":[{"name":"Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust University of Cambridge  Cambridge UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sally","family":"John","sequence":"additional","affiliation":[{"name":"Informatics &amp; Predictive Sciences Bristol Myers Squibb  Cambridge Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Karran","sequence":"additional","affiliation":[{"name":"University College London  London UK"},{"name":"Vannin Neuropharma Consulting Ltd  Canterbury UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helene A.","family":"Fachim","sequence":"additional","affiliation":[{"name":"Medicines Discovery Catapult  Macclesfield UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Imarisio","sequence":"additional","affiliation":[{"name":"Medicines Discovery Catapult  Macclesfield UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raj","family":"Long","sequence":"additional","affiliation":[{"name":"Senior Advisor Consultant Gates Ventures  Kirkland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte","family":"Teunissen","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine Neurochemistry Laboratory Amsterdam UMC  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah P.","family":"Slight","sequence":"additional","affiliation":[{"name":"School of Pharmacy Newcastle University  Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Mummery","sequence":"additional","affiliation":[{"name":"Dementia Research Centre Department of Neurodegenerative Disease UCL Queen Square Institute of Neurology University College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Hardy","sequence":"additional","affiliation":[{"name":"Deputy\u2010chair of the Scientific Advisory Board of the Dementia Goals Programme Department of Neurodegenerative Disease UK Dementia Research Institute Centre at University College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,5]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"GOV.UK.Dame Barbara Windsor dementia goals\u2014GOV.UK. 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