{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T05:12:37Z","timestamp":1788671557897,"version":"build-2803163510"},"reference-count":40,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T00:00:00Z","timestamp":1787270400000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["alz-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Alzheimer's &amp; Dementia"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>INTRODUCTION<\/jats:title>\n                    <jats:p>Type 2 diabetes (T2D) and obesity are among the most important risk factors for dementia. Although weight loss is an important preventive strategy, the impact of metabolic and bariatric surgery (MBS) on dementia risk remains contradictory.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>We conducted a propensity score matched study using nationwide, high\u2010quality clinical registries to compare the outcomes in patients with obesity and T2D who underwent MBS with matched controls who did not undergo surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>Over a mean follow\u2010up of 9 years, MBS was associated with a reduced risk of dementia (15\u2010year cumulative incidence 1.8%\u00a0vs. 2.7%, subdistribution hazard ratio [SHR] 0.60, 95% CI 0.47\u20130.76). The incidence was lower for Alzheimer's disease (1.2%\u00a0vs. 1.9%, SHR 0.56, 95% CI 0.41\u20130.76) and vascular dementia (0.4%\u00a0vs. 0.7%, SHR 0.49, 95% CI 0.29\u20130.85), but increased for alcohol\u2010related dementia (0.2%\u00a0vs. 0.04%, SHR 3.67, 95%CI 1.33\u201310.14).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DISCUSSION<\/jats:title>\n                    <jats:p>These findings suggest that the collected long\u2010term effects of MBS may reduce the risk of developing dementia in individuals with obesity and T2D.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/alz.71802","type":"journal-article","created":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T06:54:57Z","timestamp":1787381697000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The effects of bariatric surgery on dementia in patients with diabetes and obesity"],"prefix":"10.1002","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9189-0093","authenticated-orcid":false,"given":"Erik","family":"Stenberg","sequence":"first","affiliation":[{"name":"Department of Surgery, Faculty of Medicine and Health \u00d6rebro University  \u00d6rebro Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Cao","sequence":"additional","affiliation":[{"name":"Clinical Epidemiology and Biostatistics, School of Medical Sciences, Faculty of Medicine and Health \u00d6rebro University  \u00d6rebro Sweden"},{"name":"Unit of Integrative Epidemiology Institute of Environmental Medicine, Karolinska Institutet  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bj\u00f6rn","family":"Eliasson","sequence":"additional","affiliation":[{"name":"Department of Medicine Sahlgrenska University Hospital  Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik","family":"N\u00e4slund","sequence":"additional","affiliation":[{"name":"Division of Surgery, Department of Clinical Sciences Danderyd Hospital, Karolinska Institutet  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,21]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"GBD 2019 Dementia Forecasting Collaborators.Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study2019.Lancet Public Health. 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