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Quercetin, a flavonoid abundant in vegetables and fruits, is gaining attention for its antioxidant, anti\u2010inflammatory, and antiapoptotic properties. It regulates signaling pathways such as nuclear factor\u2010\u03baB (NF\u2010\u03baB), sirtuins, and phosphatidylinositol 3\u2010kinase\/protein kinase B (PI3K\/Akt). These pathways are essential for cellular survival, inflammation regulation, and apoptosis. Preclinical and clinical studies have shown that quercetin improves symptoms and pathology in neurodegenerative models, indicating promising outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The study explores the potential of incorporating laboratory research into practical medical treatment, focusing on quercetin\u2018s neuroprotective effects on NDs and its optimal dosage.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ame2.12551","type":"journal-article","created":{"date-parts":[[2025,1,22]],"date-time":"2025-01-22T23:00:43Z","timestamp":1737586843000},"page":"798-818","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Targeting signaling pathways in neurodegenerative diseases: Quercetin's cellular and molecular mechanisms for neuroprotection"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6949-8837","authenticated-orcid":false,"given":"Md. 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