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Animal models are essential in lung cancer research as they accurately replicate the biological characteristics and treatment outcomes seen in human diseases. Currently, various lung cancer models have been established, including chemical induction models, orthotopic transplantation models, ectopic transplantation models, metastasis models, and gene editing mouse models. Additionally, lung cancer grafts can be categorized into two types: tissue\u2010based and cell\u2010based grafts. This paper summarizes the phenotypes, advantages, and disadvantages of various induction methods based on their modeling techniques. 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